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Lymph node and tumor-associated PD-L1+ macrophages antagonize dendritic cell vaccines by suppressing CD8+ T cells
Jenny Sprooten, Isaure Vanmeerbeek, Angeliki Datsi, Jannes Govaerts, Stefan Naulaerts, Raquel S. Laureano, Daniel Borràs, Anna Calvet, Vanshika Malviya, Marc Kuballa, Jörg Felsberg, Michael Sabel, Marion Rapp, Christiane B. Knobbe‐Thomsen, Peng Liu, Liwei Zhao, Oliver Kepp, Louis Boon, Sabine Tejpar, Jannie Borst, Guido Guido Kroemer, Susan Schlenner, Steven De Vleeschouwer, Rüdiger V. Sorg, Abhishek D. Garg (2024). Lymph node and tumor-associated PD-L1+ macrophages antagonize dendritic cell vaccines by suppressing CD8+ T cells. , 5(1), DOI: https://doi.org/10.1016/j.xcrm.2023.101377.
Article74 days agoA lymph node-to-tumour PDL1<sup>+</sup>macrophage circuit antagonizes dendritic cell immunotherapy
Jenny Sprooten, Isaure Vanmeerbeek, Angeliki Datsi, Jannes Govaerts, Daniel Borràs, Stefan Naulaerts, Raquel S. Laureano, Anna Calvet, Marc Kuballa, Michael Sabel, Marion Rapp, Christiane B. Knobbe‐Thomsen, Peng Liu, Liwei Zhao, Oliver Kepp, Guido Guido Kroemer, Louis Boon, Sabine Tejpar, Jannie Borst, Susan Schlenner, Steven De Vleeschouwer, Rüdiger V. Sorg, Abhishek D. Garg (2023). A lymph node-to-tumour PDL1<sup>+</sup>macrophage circuit antagonizes dendritic cell immunotherapy. , DOI: https://doi.org/10.1101/2023.03.14.532534.
Preprint74 days ago