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Get Free AccessCurrent immunotherapies provide limited benefits against T cell-depleted tumors, calling for therapeutic innovation. Using multi-omics integration of cancer patient data, we predict a type I interferon (IFN) response
Jenny Sprooten, Isaure Vanmeerbeek, Angeliki Datsi, Jannes Govaerts, Stefan Naulaerts, Raquel S. Laureano, Daniel Borràs, Anna Calvet, Vanshika Malviya, Marc Kuballa, Jörg Felsberg, Michael Sabel, Marion Rapp, Christiane B. Knobbe‐Thomsen, Peng Liu, Liwei Zhao, Oliver Kepp, Louis Boon, Sabine Tejpar, Jannie Borst, Guido Guido Kroemer, Susan Schlenner, Steven De Vleeschouwer, Rüdiger V. Sorg, Abhishek D. Garg (2024). Lymph node and tumor-associated PD-L1+ macrophages antagonize dendritic cell vaccines by suppressing CD8+ T cells. , 5(1), DOI: https://doi.org/10.1016/j.xcrm.2023.101377.
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Type
Article
Year
2024
Authors
25
Datasets
0
Total Files
0
Language
en
DOI
https://doi.org/10.1016/j.xcrm.2023.101377
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