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Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages
Eva M. Pålsson‐McDermott, Annie M. Curtis, Gautam Goel, Mario A. Lauterbach, Frederick J. Sheedy, Laura E. Gleeson, Mirjam W.M. van den Bosch, Susan R. Quinn, Raquel Domingo-Fernandéz, Daniel Johnston, Jian‐kang Jiang, William J. Israelsen, Joseph Keane, Craig J. Thomas, Clary B. Clish, Matthew G. Vander Heiden, Ramnik J. Xavier, Luke O'neill (2015). Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages. Cell Metabolism, 21(1), pp. 65-80, DOI: 10.1016/j.cmet.2014.12.005.
Article167 days agoCutting Edge: <i>Mycobacterium tuberculosis</i> Induces Aerobic Glycolysis in Human Alveolar Macrophages That Is Required for Control of Intracellular Bacillary Replication
Laura E. Gleeson, Frederick J. Sheedy, Eva M. Pålsson‐McDermott, Denise Triglia, Seónadh M. O’Leary, Mary P. O’Sullivan, Luke O'neill, Joseph Keane (2016). Cutting Edge: <i>Mycobacterium tuberculosis</i> Induces Aerobic Glycolysis in Human Alveolar Macrophages That Is Required for Control of Intracellular Bacillary Replication. The Journal of Immunology, 196(6), pp. 2444-2449, DOI: 10.4049/jimmunol.1501612.
Article167 days agoA Common Variant in the Adaptor Mal Regulates Interferon Gamma Signaling
Clíona Ní Cheallaigh, Frederick J. Sheedy, James Harris, Natalia Muñoz‐Wolf, Jinhee Lee, Kim West, Eva M. Pålsson‐McDermott, Alicia Smyth, Laura E. Gleeson, Michelle M. Coleman, Núria Martínez, Claire H. Hearnden, Graham A. Tynan, Elizabeth C. Carroll, Sarah A. Jones, Sinéad C. Corr, Nicholas J. Bernard, Mark Hughes, Sarah E. Corcoran, Mary P. O’Sullivan, Ciara M. Fallon, Hardy Kornfeld, Douglas T. Golenbock, Stephen V. Gordon, Luke O'neill, Ed C. Lavelle, Joseph Keane (2016). A Common Variant in the Adaptor Mal Regulates Interferon Gamma Signaling. Immunity, 44(2), pp. 368-379, DOI: 10.1016/j.immuni.2016.01.019.
Article167 days agoPyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages
Eva M. Pålsson‐McDermott, Annie M. Curtis, Gautam Goel, Mario A. Lauterbach, Frederick J. Sheedy, Laura E. Gleeson, Mirjam W.M. van den Bosch, Susan R. Quinn, Raquel Domingo-Fernandéz, Daniel Johnston, Jian‐kang Jiang, William J. Israelsen, Joseph Keane, Craig J. Thomas, Clary B. Clish, Matthew G. Vander Heiden, Ramnik J. Xavier, Luke O'neill (2015). Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages. , 21 (2), DOI: https://doi.org/10.1016/j.cmet.2015.01.017.
Corrigendum44 days ago