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  5. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1

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Article
English
2018

Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1

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0 Files

English
2018
Nature
Vol 556 (7699)
DOI: 10.1038/nature25986

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Luke O'neill
Luke O'neill

Trinity College Dublin

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Evanna L. Mills
Dylan G. Ryan
Hiran A. Prag
+32 more

Abstract

No abstract is provided for this article.

How to cite this publication

Evanna L. Mills, Dylan G. Ryan, Hiran A. Prag, Dina Dikovskaya, Deepthi Menon, Zbigniew Zasłona, Mark P. Jedrychowski, Ana S.H. Costa, Maureen Higgins, Emily Hams, John Szpyt, Marah C. Runtsch, Martin S. King, Joanna F. McGouran, Román Fischer, Benedikt M. Kessler, Anne F. McGettrick, Mark Hughes, Richard G. Carroll, Lee M. Booty, Elena V. Knatko, Paul J. Meakin, Michael L.J. Ashford, Louise K. Modis, Gino Brunori, Daniel C. Sévin, Padraic G. Fallon, Stuart T. Caldwell, Edmund R.S. Kunji, Edward T. Chouchani, Christian Frezza, Albena T. Dinkova‐Kostova, Richard C. Hartley, Michael P. Murphy, Luke O'neill (2018). Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1. Nature, 556(7699), pp. 113-117, DOI: 10.1038/nature25986.

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Publication Details

Type

Article

Year

2018

Authors

35

Datasets

0

Total Files

0

Language

English

Journal

Nature

DOI

10.1038/nature25986

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