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I am an experienced cancer biologist, a Laboratory Head at St Vincent's Institute of Medical Research and a Victorian Cancer Agency Mid-Career Research Fellow (2020-2024). I use…
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The last 5 uploaded publications
Local nucleolar surveillance mechanisms maintain rDNA stability
Ruofei Liu, Jiachen Xuan, Jian Pan, Shalini Sundramurthi Chelliah, Rhynelle Dmello, Karla J. Cowley, Sergio Mendez, Y. C. Zhang, Kezia Gitareja, Matthew Wakefield, Andrew J. Deans, Clare L. Scott, Keefe T. Chan, Kaylene J. Simpson, Jianfeng Kang, Elaine Sanij (2025). Local nucleolar surveillance mechanisms maintain rDNA stability. , DOI: https://doi.org/10.1101/2025.01.20.633984.
Preprint61 days agoThe role of STK11/LKB1 in cancer biology: implications for ovarian tumorigenesis and progression
Jian Kang, Stefania Gallucci, Jian Pan, Jonathan S. Oakhill, Elaine Sanij (2024). The role of STK11/LKB1 in cancer biology: implications for ovarian tumorigenesis and progression. , 12, DOI: https://doi.org/10.3389/fcell.2024.1449543.
Article61 days agoTargeting the ribosome to treat multiple myeloma
Kylee Maclachlan, Kezia Gitareja, Jian Kang, Andrew Cuddihy, Yuxi Cao, Nadine Hein, Carleen Cullinane, Ching‐Seng Ang, Natalie Brajanovski, Richard B. Pearson, Amit Khot, Elaine Sanij, Ross D. Hannan, Gretchen Poortinga, Simon J. Harrison (2024). Targeting the ribosome to treat multiple myeloma. , 32(1), DOI: https://doi.org/10.1016/j.omton.2024.200771.
Article61 days agoERG and c-MYC regulate a critical gene network in BCR::ABL1-driven B cell acute lymphoblastic leukemia
Kira Behrens, Natalie Brajanovski, Zhen Xu, Elizabeth M. Viney, Ladina DiRago, Soroor Hediyeh-zadeh, Melissa J. Davis, Richard B. Pearson, Elaine Sanij, Warren S. Alexander, Ashley P. Ng (2024). ERG and c-MYC regulate a critical gene network in BCR::ABL1-driven B cell acute lymphoblastic leukemia. , 10(10), DOI: https://doi.org/10.1126/sciadv.adj8803.
Article61 days agoAbstract PR005: CX-5461 sensitizes DNA damage repair-proficient castrate-resistant prostate cancer to PARP inhibition
Mitchell G. Lawrence, Laura H. Porter, Nicholas Choo, Elaine Sanij, Renea A. Taylor, Richard B. Pearson, Kaylene J. Simpson, Ross D. Hannan, Shahneen Sandhu, Luc Furic (2024). Abstract PR005: CX-5461 sensitizes DNA damage repair-proficient castrate-resistant prostate cancer to PARP inhibition. , 23(6_Supplement), DOI: https://doi.org/10.1158/1538-8514.synthleth24-pr005.
Article61 days ago