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The last 5 uploaded publications
Recognition of 5′ Triphosphate by RIG-I Helicase Requires Short Blunt Double-Stranded RNA as Contained in Panhandle of Negative-Strand Virus
Martin Schlee, Andreas Roth, Veit Hornung, Cristina Amparo Hagmann, Vera Wimmenauer, Winfried Barchet, Christoph Coch, Markus Janke, Aleksandra Mihailović, Greg Wardle, Stefan Juranek, Hiroki Kato, Taro Kawai, Hendrik Poeck, Katherine A. Fitzgerald, Osamu Takeuchi, Akira Shizuo, Thomas Tuschl, Eicke Latz, János Ludwig, Gunther Hartmann (2009). Recognition of 5′ Triphosphate by RIG-I Helicase Requires Short Blunt Double-Stranded RNA as Contained in Panhandle of Negative-Strand Virus. Immunity, 31(1), pp. 25-34, DOI: 10.1016/j.immuni.2009.05.008.
Article178 days agoThe myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction
Daniel C. Rowe, Anne F. McGettrick, Eicke Latz, Brian G. Monks, Nicholas J. Gay, Masahiro Yamamoto, Akira Shizuo, Luke O'neill, Katherine A. Fitzgerald, Douglas T. Golenbock (2006). The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction. Proceedings of the National Academy of Sciences, 103(16), pp. 6299-6304, DOI: 10.1073/pnas.0510041103.
Article173 days agoInvolvement of Toll-like Receptor (TLR) 2 and TLR4 in Cell Activation by Mannuronic Acid Polymers
Trude H. Flo, Liv Ryan, Eicke Latz, Osamu Takeuchi, Brian G. Monks, Egil Lien, Øyvind Halaas, Akira Shizuo, Gudmund Skjåk‐Bræk, Douglas T. Golenbock, Terje Espevik (2002). Involvement of Toll-like Receptor (TLR) 2 and TLR4 in Cell Activation by Mannuronic Acid Polymers. Journal of Biological Chemistry, 277(38), pp. 35489-35495, DOI: 10.1074/jbc.m201366200.
Article173 days agoTLR7/8 stress response drives histiocytosis in SLC29A3 disorders
Takuma Shibata, Ryota Sato, Masato Taoka, Shin-ichiroh Saitoh, Mayumi Komine, Kiyoshi Yamaguchi, Susumu Goyama, Yuji Motoi, Jiro Kitaura, Kumi Izawa, Yoshio Yamauchi, Yumiko Tsukamoto, Takeshi Ichinohe, E. Fujita, Ryosuke Hiranuma, Ryutaro Fukui, Yoichi Furukawa, Toshio Kitamura, Toshiyuki Takai, Arinobu Tojo, Mamitaro Ohtsuki, Umeharu Ohto, Toshiyuki Shimizu, Manabu Ozawa, Nobuaki Yoshida, Toshiaki Isobe, Eicke Latz, Kojiro Mukai, Tomohiko Taguchi, Hiroaki Hemmi, Akira Shizuo, Kensuke Miyake (2023). TLR7/8 stress response drives histiocytosis in SLC29A3 disorders. The Journal of Experimental Medicine, 220(9), DOI: 10.1084/jem.20230054.
Article167 days agoA small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases
Rebecca C. Coll, Avril A. B. Robertson, Jae Jin Chae, Sarah Higgins, Raúl Muñoz-Planillo, Marco Inserra, Irina Vetter, Lara S. Dungan, Brian G. Monks, Andrea Stutz, Daniel E. Croker, Mark S. Butler, Moritz Haneklaus, Caroline E. Sutton, Gabriel Núñez, Eicke Latz, Daniel L. Kastner, Kingston H. G. Mills, Seth L. Masters, Kate Schroder, Matthew A. Cooper, Luke O'neill (2015). A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases. Nature Medicine, 21(3), pp. 248-255, DOI: 10.1038/nm.3806.
Article167 days ago