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A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release
Huan Yang, Hulda S. Hreggvidsdottir, Karin Palmblad, Haichao Wang, Mahendar Ochani, Jianhua Li, Ben Lü, Sangeeta S. Chavan, Mauricio Rosas‐Ballina, Yousef Al‐Abed, Akira Shizuo, Angelika Bierhaus, Helena Erlandsson-Harris, Jan Andersson, Kevin J. Tracey (2010). A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release. Proceedings of the National Academy of Sciences, 107(26), pp. 11942-11947, DOI: 10.1073/pnas.1003893107.
Article179 days agoROLE OF TOLL-LIKE RECEPTORS 2 AND 4, AND THE RECEPTOR FOR ADVANCED GLYCATION END PRODUCTS IN HIGH-MOBILITY GROUP BOX 1-INDUCED INFLAMMATION IN VIVO
Marieke A. D. van Zoelen, Huan Yang, Sandrine Florquin, Joost C.M. Meijers, Akira Shizuo, Bernd Arnold, Peter P. Nawroth, Angelika Bierhaus, Kevin J. Tracey, Tom van der Poll (2009). ROLE OF TOLL-LIKE RECEPTORS 2 AND 4, AND THE RECEPTOR FOR ADVANCED GLYCATION END PRODUCTS IN HIGH-MOBILITY GROUP BOX 1-INDUCED INFLAMMATION IN VIVO. Shock, 31(3), pp. 280-284, DOI: 10.1097/shk.0b013e318186262d.
Article174 days agoToll-like receptor 4–dependent contribution of the immune system to anticancer chemotherapy and radiotherapy
Lionel Apétoh, François Ghiringhelli, Antoine Tesnière, Michel Obéid, Carla Ortiz, Alfredo Criollo, Grégoire Mignot, Maria Chiara Maiuri, Evelyn Ullrich, Patrick Saulnier, Huan Yang, Sebastián Amigorena, Bernard Ryffel, Franck J. Barrat, Paul Säftig, Françis Lévi, Rosette Lidereau, Catherine Noguès, Jean‐Paul Mira, Agnès Chompret, V. Joulin, Françoise Clavel‐Chapelon, Jean Bourhis, Fabrice André, Suzette Delaloge, Thomas Tursz, Guido Guido Kroemer, Laurence Zitvogel (2007). Toll-like receptor 4–dependent contribution of the immune system to anticancer chemotherapy and radiotherapy. , 13(9), DOI: https://doi.org/10.1038/nm1622.
Article73 days ago