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Succinate is an inflammatory signal that induces IL-1β through HIF-1α
Gillian M. Tannahill, Annie M. Curtis, Juraj Adamik, Eva M. Pålsson‐McDermott, Anne F. McGettrick, Gautam Goel, Christian Frezza, Nicholas J. Bernard, Beth Kelly, Niamh H. Foley, Liang Zheng, Agnès Gardet, Zhen Tong, S. S. Jany, Sinéad C. Corr, Moritz Haneklaus, Brian E. Caffrey, Kerry A. Pierce, Sarah R. Walmsley, Federico C. Beasley, Eoin P. Cummins, Victor Nizet, Moira K. B. Whyte, Cormac T. Taylor, Hening Lin, Seth L. Masters, Eyal Gottlieb, Vincent P. Kelly, Clary B. Clish, Philip E. Auron, Ramnik J. Xavier, Luke O'neill (2013). Succinate is an inflammatory signal that induces IL-1β through HIF-1α. Nature, 496(7444), pp. 238-242, DOI: 10.1038/nature11986.
Article167 days agoDistinct Mechanisms for Induction and Tolerance Regulate the Immediate Early Genes Encoding Interleukin 1β and Tumor Necrosis Factor α
Juraj Adamik, Kent Z.Q. Wang, Sebnem Unlu, An-Jey A. Su, Gillian M. Tannahill, Deborah L. Galson, Luke O'neill, Philip E. Auron (2013). Distinct Mechanisms for Induction and Tolerance Regulate the Immediate Early Genes Encoding Interleukin 1β and Tumor Necrosis Factor α. PLoS ONE, 8(8), pp. e70622-e70622, DOI: 10.1371/journal.pone.0070622.
Article167 days ago2
Juraj Adamik, Gillian M. Tannahill, An-Jey A. Su, Luke O'neill, Deborah L. Galson, Philip E. Auron (2013). 2. Cytokine, 63(3), pp. 243-243, DOI: 10.1016/j.cyto.2013.06.005.
Article167 days agoThe P‐TEFb‐dependent Gene Coding for IL‐1β is More Sensitive to Cellular Metabolism than that of the BRD4‐dependent TNFα‐coding Gene
Juraj Adamik, Gillian M. Tannahill, An-Jey A. Su, Luke O'neill, Deborah L. Galson, Philip E. Auron (2013). The P‐TEFb‐dependent Gene Coding for IL‐1β is More Sensitive to Cellular Metabolism than that of the BRD4‐dependent TNFα‐coding Gene. The FASEB Journal, 27(S1), DOI: 10.1096/fasebj.27.1_supplement.769.8.
Article167 days ago2
Juraj Adamik, Gillian M. Tannahill, An-Jey A. Su, Luke O'neill, Deborah L. Galson, Philip E. Auron (2013). 2. Cytokine, 63(3), pp. 243-243, DOI: 10.1016/j.cyto.2013.06.005.
Article144 days ago