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The last 5 uploaded publications
Epigenetic inactivation of the 5-methylcytosine RNA methyltransferase NSUN7 is associated with clinical outcome and therapeutic vulnerability in liver cancer
Vanessa Ortiz-Barahona, Marta Soler, Verónica Dávalos, Carlos A. García‐Prieto, Maxime Janin, Fernando Setién, Irene Fernández-Rebollo, Joan Josep Bech‐Serra, Carolina de la Torre, Sònia Guil, Alberto Villanueva, Peihong Zhang, Li Yang, Marco Guarnacci, Ulrike Schümann, Thomas Preiß, Ugne Balaseviciute, Robert Montal, Josep M. Llovet, Manel Esteller (2023). Epigenetic inactivation of the 5-methylcytosine RNA methyltransferase NSUN7 is associated with clinical outcome and therapeutic vulnerability in liver cancer. Molecular Cancer, 22(1), DOI: 10.1186/s12943-023-01785-z.
Article145 days agoGlobal Shift in Alternative Splicing and Therapeutic Susceptibilities in Leukemia Driven by METTL3 Overexpression
Maxime Janin, Manel Esteller (2023). Global Shift in Alternative Splicing and Therapeutic Susceptibilities in Leukemia Driven by METTL3 Overexpression. , 4(3), DOI: https://doi.org/10.1158/2643-3230.bcd-23-0035.
Letter74 days agoCancer metastasis under the magnifying glass of epigenetics and epitranscriptomics
Maxime Janin, Verónica Dávalos, Manel Esteller (2023). Cancer metastasis under the magnifying glass of epigenetics and epitranscriptomics. , 42(4), DOI: https://doi.org/10.1007/s10555-023-10120-3.
Article74 days agoAbstract 153: Epigenetic loss of NSUN5 in glioma drives a global protein synthesis depletion along with the emergence of a stress adaptive translational program
Vanessa Ortiz Barahona, Maxime Janin, Manel Esteller (2020). Abstract 153: Epigenetic loss of NSUN5 in glioma drives a global protein synthesis depletion along with the emergence of a stress adaptive translational program. , 80(16_Supplement), DOI: https://doi.org/10.1158/1538-7445.am2020-153.
Article74 days agoAbstract 5416: Positioning the NQO1-bioactivatable drug isobutyl-deoxynyboquinone in diffuse intrinsic pontine glioma (DIPG): an exceptional therapeutic opportunity in pediatric brain tumor
Maxime Janin, Vanessa Ortiz Barahona, Pere Llinas Arias, Carolina de la Torre, Ángel M. Carcaboso, Andrés Morales La Madrid, Paul J. Hergenrother, Manel Esteller (2020). Abstract 5416: Positioning the NQO1-bioactivatable drug isobutyl-deoxynyboquinone in diffuse intrinsic pontine glioma (DIPG): an exceptional therapeutic opportunity in pediatric brain tumor. , 80(16_Supplement), DOI: https://doi.org/10.1158/1538-7445.am2020-5416.
Article74 days ago