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Abstract 2210: Microbiome profiling reveals that fecal microbiota transplantation (FMT) modulates response and toxicity when combined with immunotherapy in patients with lung cancer and melanoma (FMT-LUMINate NCT04951583)
Sreya Duttagupta, Meriem Messaoudene, Rahima Jamal, Catalin Mihalcioiu, Nicolas Marcoux, Sebastian Hunter, Gianmarco Piccinno, Michal Punčochář, Karl Bélanger, Mustapha Tehfé, Normand Blais, Scott Owen, Jacques Raphael, Jade Maillou, Yongjia Hu, Myriam Benlaïfaoui, Somayeh Nilli, John Lenehan, Wiam Belkaïd, Seema Nair Parvathy, Diogjena Katerina Prifti, Marine Fidelle, Seunghee Kim‐Schulze, Thomas U. Marron, Sylvère Durand, Guido Guido Kroemer, Nicola Segata, Lisa Derosa, Laurence Zitvogel, Antoine Desîlets, Michael E. Silverman, Saman MalekiVareki, Bertrand Routy, Arielle Elkrief (2025). Abstract 2210: Microbiome profiling reveals that fecal microbiota transplantation (FMT) modulates response and toxicity when combined with immunotherapy in patients with lung cancer and melanoma (FMT-LUMINate NCT04951583). , 85(8_Supplement_1), DOI: https://doi.org/10.1158/1538-7445.am2025-2210.
Article73 days agoBenzodiazepines interfere with the efficacy of pembrolizumab-based cancer immunotherapy. Results of a nationwide cohort study including over 50,000 participants with advanced lung cancer
Léa Montégut, Adrien Rousseau, Cinzia Ungolo, Lisa Derosa, Marine Fidelle, Carolina Alves Costa Silva, Bertrand Routy, Laurence Zitvogel, Benjamin Besse, Edoardo Pasolli, Guido Guido Kroemer (2025). Benzodiazepines interfere with the efficacy of pembrolizumab-based cancer immunotherapy. Results of a nationwide cohort study including over 50,000 participants with advanced lung cancer. , 14(1), DOI: https://doi.org/10.1080/2162402x.2025.2528955.
Article73 days agoAbstract 6423: Multiomic functional biomarkers for predicting the transition from inflammation to cancer
Suzette Delaloge, Kuznetsova Tv, David Boulate, Laurence Zitvogel, Marine Fidelle, Déborah Suissa, Aline Renneville, Tarek Ben-Ahmed, Sylvère Durand, Olivier Caron, Olaf Mercier, Lisa Derosa, Birgit Geoerger, Guido Guido Kroemer, Damien Drubay (2025). Abstract 6423: Multiomic functional biomarkers for predicting the transition from inflammation to cancer. , 85(8_Supplement_1), DOI: https://doi.org/10.1158/1538-7445.am2025-6423.
Article73 days agoLow-dose irradiation of the gut improves the efficacy of PD-L1 blockade in metastatic cancer patients
Jianzhou Chen, Antonin Lévy, Ai-Ling Tian, Xuehan Huang, Guoxin Cai, Marine Fidelle, Conrad Rauber, Pierre Ly, Eugénie Pizzato, Lisa Sitterlé, Gianmarco Piccinno, Peng Liu, Sylvère Durand, Misha Mao, Liwei Zhao, Valerio Iebba, Hannah Felchle, Anne-Laure Mallard de La Varende, Julius C. Fischer, Simon Thomas, Tim F. Greten, Jennifer Jones, Cecilia Monge, Sandra Demaria, Silvia C. Formenti, Lorenzo Belluomini, V. Dionisi, Christophe Massard, Pierre‐Yves Blanchard, Charlotte Robert, Clément Quevrin, Eloise Lopes, Céline Clémenson, Michele Mondini, Lydia Meziani, Yizhou Zhan, Chengbing Zeng, Qingxin Cai, Daphné Morel, Roger Sun, Pierre-Antoine Laurent, Monica Mangoni, Vanessa Di Cataldo, C. Arilli, Maike Trommer, Simone Wegen, Sebastian Neppl, Rachel P. Riechelmann, Marcos Pedro Guedes Camandaroba, Elson Santos Neto, Pierre‐Edouard Fournier, Nicola Segata, Peter Holíček, Lorenzo Galluzzi, Aitziber Buqué, Carolina Alves Costa Silva, Lisa Derosa, Guido Guido Kroemer, Chuangzhen Chen, Laurence Zitvogel, Éric Deutsch (2025). Low-dose irradiation of the gut improves the efficacy of PD-L1 blockade in metastatic cancer patients. , 43(3), DOI: https://doi.org/10.1016/j.ccell.2025.02.010.
Article73 days agoImpact of the ONCOBIOME network in cancer microbiome research
Laurence Zitvogel, Lisa Derosa, Bertrand Routy, Sibylle Loibl, Lucie Heinzerling, I. Jolanda M. de Vries, Lars Engstrand, Nicola Segata, Guido Guido Kroemer (2025). Impact of the ONCOBIOME network in cancer microbiome research. , DOI: https://doi.org/10.1038/s41591-025-03608-8.
Article73 days ago