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The last 5 uploaded publications
Succinate is an inflammatory signal that induces IL-1β through HIF-1α
Gillian M. Tannahill, Annie M. Curtis, Juraj Adamik, Eva M. Pålsson‐McDermott, Anne F. McGettrick, Gautam Goel, Christian Frezza, Nicholas J. Bernard, Beth Kelly, Niamh H. Foley, Liang Zheng, Agnès Gardet, Zhen Tong, S. S. Jany, Sinéad C. Corr, Moritz Haneklaus, Brian E. Caffrey, Kerry A. Pierce, Sarah R. Walmsley, Federico C. Beasley, Eoin P. Cummins, Victor Nizet, Moira K. B. Whyte, Cormac T. Taylor, Hening Lin, Seth L. Masters, Eyal Gottlieb, Vincent P. Kelly, Clary B. Clish, Philip E. Auron, Ramnik J. Xavier, Luke O'neill (2013). Succinate is an inflammatory signal that induces IL-1β through HIF-1α. Nature, 496(7444), pp. 238-242, DOI: 10.1038/nature11986.
Article167 days agoA Common Variant in the Adaptor Mal Regulates Interferon Gamma Signaling
Clíona Ní Cheallaigh, Frederick J. Sheedy, James Harris, Natalia Muñoz‐Wolf, Jinhee Lee, Kim West, Eva M. Pålsson‐McDermott, Alicia Smyth, Laura E. Gleeson, Michelle M. Coleman, Núria Martínez, Claire H. Hearnden, Graham A. Tynan, Elizabeth C. Carroll, Sarah A. Jones, Sinéad C. Corr, Nicholas J. Bernard, Mark Hughes, Sarah E. Corcoran, Mary P. O’Sullivan, Ciara M. Fallon, Hardy Kornfeld, Douglas T. Golenbock, Stephen V. Gordon, Luke O'neill, Ed C. Lavelle, Joseph Keane (2016). A Common Variant in the Adaptor Mal Regulates Interferon Gamma Signaling. Immunity, 44(2), pp. 368-379, DOI: 10.1016/j.immuni.2016.01.019.
Article167 days agoMal, more than a bridge to MyD88
Nicholas J. Bernard, Luke O'neill (2013). Mal, more than a bridge to MyD88. IUBMB Life, 65(9), pp. 777-786, DOI: 10.1002/iub.1201.
Article167 days agoMyD88 adaptor-like (Mal) functions in the epithelial barrier and contributes to intestinal integrity via protein kinase C
Sinéad C. Corr, Eva M. Pålsson‐McDermott, Irina Grishina, Sean Barry, Gabriella Aviello, Nicholas J. Bernard, Patrick G. Casey, Joseph B. J. Ward, Stephen J. Keely, Satya Dandekar, Padraic G. Fallon, Luke O'neill (2013). MyD88 adaptor-like (Mal) functions in the epithelial barrier and contributes to intestinal integrity via protein kinase C. Mucosal Immunology, 7(1), pp. 57-67, DOI: 10.1038/mi.2013.24.
Article167 days agoA critical role for the TLR signaling adapter Mal in alveolar macrophage-mediated protection against Bordetella pertussis
Nicholas J. Bernard, Conor M. Finlay, Gillian M. Tannahill, Joseph P. Cassidy, Luke O'neill, Kingston H. G. Mills (2014). A critical role for the TLR signaling adapter Mal in alveolar macrophage-mediated protection against Bordetella pertussis. Mucosal Immunology, 8(5), pp. 982-992, DOI: 10.1038/mi.2014.125.
Article167 days ago