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The last 5 uploaded publications
Regulation of PRMT5–MDM4 axis is critical in the response to CDK4/6 inhibitors in melanoma
Shatha AbuHammad, Carleen Cullinane, Claire Martin, Zoe Bacolas, Teresa Ward, Huiqin Chen, Alison Slater, Kerry Ardley, Laura Kirby, Keefe T. Chan, Natalie Brajanovski, Lorey Smith, Aparna D. Rao, Emily J. Lelliott, Margarete Kleinschmidt, Ismael A. Vergara, Anthony T. Papenfuss, Peter K. H. Lau, Prerana Ghosh, Sue Haupt, Ygal Haupt, Elaine Sanij, Gretchen Poortinga, Richard B. Pearson, Hendrik Falk, David J. Curtis, Paul A. Stupple, Mark Devlin, Ian P. Street, Michael A. Davies, Grant A. McArthur, Karen E. Sheppard (2019). Regulation of PRMT5–MDM4 axis is critical in the response to CDK4/6 inhibitors in melanoma. , 116(36), DOI: https://doi.org/10.1073/pnas.1901323116.
Article62 days agoMelanoma brain metastases that progress on BRAF-MEK inhibitors demonstrate resistance to ipilimumab-nivolumab that is associated with the Innate PD-1 Resistance Signature (IPRES)
Peter K. H. Lau, Breon Feran, Lorey Smith, Arian Lasocki, Ramyar Molania, Kortnye Smith, Alison M. Weppler, Christopher Angel, Damien Kee, Prachi Bhave, Belinda Lee, Richard J. Young, Amir Iravani, Hanxian Aw Yeang, Ismael A. Vergara, David L. Kok, Kate Drummond, Paul J. Neeson, Karen E. Sheppard, Anthony T. Papenfuss, Benjamin Solomon, Shahneen Sandhu, Grant A. McArthur (2021). Melanoma brain metastases that progress on BRAF-MEK inhibitors demonstrate resistance to ipilimumab-nivolumab that is associated with the Innate PD-1 Resistance Signature (IPRES). , 9(10), DOI: https://doi.org/10.1136/jitc-2021-002995.
Article62 days ago1079MO Progression of BRAF mutant CNS metastases are associated with a transcriptional network bearing similarities with the innate PD-1 resistant signature (IPRES)
Peter K. H. Lau, Breon Feran, Lorey Smith, Arian Lasocki, Ramyar Molania, Kortnye Smith, Alison M. Weppler, Christopher Angel, Damien Kee, Prachi Bhave, Belinda Lee, Han Xian Aw Yeang, Ismael A. Vergara, David L. Kok, Katharine J. Drummond, Paul J. Neeson, Karen E. Sheppard, Anthony T. Papenfuss, Shahneen Sandhu, Grant A. McArthur (2020). 1079MO Progression of BRAF mutant CNS metastases are associated with a transcriptional network bearing similarities with the innate PD-1 resistant signature (IPRES). , 31, DOI: https://doi.org/10.1016/j.annonc.2020.08.1203.
Article62 days ago1079MO Progression of BRAF mutant CNS metastases are associated with a transcriptional network bearing similarities with the innate PD-1 resistant signature (IPRES)
Peter K. H. Lau, Breon Feran, Lorey Smith, Arian Lasocki, Ramyar Molania, Kortnye Smith, Alison M. Weppler, Christopher Angel, Damien Kee, Prachi Bhave, Belinda Lee, Han Xian Aw Yeang, Ismael A. Vergara, David L. Kok, Katharine J. Drummond, Paul J. Neeson, Karen E. Sheppard, Anthony T. Papenfuss, Shahneen Sandhu, Grant A. McArthur (2020). 1079MO Progression of BRAF mutant CNS metastases are associated with a transcriptional network bearing similarities with the innate PD-1 resistant signature (IPRES). , 31, DOI: https://doi.org/10.1016/j.annonc.2020.08.1203.
Article62 days agoAdaptive post-transcriptional reprogramming of metabolism limits response to targeted therapy in BRAF<sup>V600</sup> melanoma
Lorey Smith, Tiffany J. Parmenter, Margarete Kleinschmidt, Eric Kusnadi, Jian Jian Kang, Claire Martin, Peter K. H. Lau, Julie Lorent, Anna Trigos, Teresa Ward, Aparna D. Rao, Emily J. Lelliott, Karen E. Sheppard, David L. Goode, Rodney J. Hicks, Tony Tiganis, Kaylene J. Simpson, Ola Larsson, Carleen Cullinane, Vihandha O. Wickramasinghe, Richard B. Pearson, Grant A. McArthur (2019). Adaptive post-transcriptional reprogramming of metabolism limits response to targeted therapy in BRAF<sup>V600</sup> melanoma. , DOI: https://doi.org/10.1101/626952.
Preprint62 days ago