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The last 5 uploaded publications
MicroRNAs: the fine-tuners of Toll-like receptor signalling
Luke O'neill, Frederick J. Sheedy, Claire E. McCoy (2011). MicroRNAs: the fine-tuners of Toll-like receptor signalling. Nature reviews. Immunology, 11(3), pp. 163-175, DOI: 10.1038/nri2957.
Article167 days agoIL-10 Inhibits miR-155 Induction by Toll-like Receptors
Claire E. McCoy, Frederick J. Sheedy, Joseph E. Qualls, Sarah Doyle, Susan R. Quinn, Peter J. Murray, Luke O'neill (2010). IL-10 Inhibits miR-155 Induction by Toll-like Receptors. Journal of Biological Chemistry, 285(27), pp. 20492-20498, DOI: 10.1074/jbc.m110.102111.
Article167 days agoA Role for TLR4 in Clostridium difficile Infection and the Recognition of Surface Layer Proteins
Anthony W. Ryan, Mark Lynch, Sinead Smith, Sylvie Amu, Hendrik J. Nel, Claire E. McCoy, Jennifer K. Dowling, Eve Draper, Vincent O’Reilly, Ciara McCarthy, Julie O’Brien, Déirdre Ní Eidhin, Mary J. O’Connell, Brian Keogh, Oliver Morton, Thomas R. Rogers, Padraic G. Fallon, Luke O'neill, Dermot Kelleher, Christine E. Loscher (2011). A Role for TLR4 in Clostridium difficile Infection and the Recognition of Surface Layer Proteins. PLoS Pathogens, 7(6), pp. e1002076-e1002076, DOI: 10.1371/journal.ppat.1002076.
Article167 days agoThe Role of Ets2 Transcription Factor in the Induction of MicroRNA-155 (miR-155) by Lipopolysaccharide and Its Targeting by Interleukin-10
Susan R. Quinn, Niamh E. Mangan, Brian E. Caffrey, Michael P. Gantier, Bryan R.G. Williams, Paul J. Hertzog, Claire E. McCoy, Luke O'neill (2013). The Role of Ets2 Transcription Factor in the Induction of MicroRNA-155 (miR-155) by Lipopolysaccharide and Its Targeting by Interleukin-10. Journal of Biological Chemistry, 289(7), pp. 4316-4325, DOI: 10.1074/jbc.m113.522730.
Article167 days agoGlucocorticoids Inhibit IRF3 Phosphorylation in Response to Toll-like Receptor-3 and -4 by Targeting TBK1 Activation
Claire E. McCoy, Susan Carpenter, Eva M. Pålsson‐McDermott, Linden J. Gearing, Luke O'neill (2008). Glucocorticoids Inhibit IRF3 Phosphorylation in Response to Toll-like Receptor-3 and -4 by Targeting TBK1 Activation. Journal of Biological Chemistry, 283(21), pp. 14277-14285, DOI: 10.1074/jbc.m709731200.
Article167 days ago