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The last 5 uploaded publications
Pipeline Olympics: continuable benchmarking of computational workflows for DNA methylation sequencing data against an experimental gold-standard
Yu‐Yu Lin, Kersten Breuer, Dieter Weichenhan, Pascal Lafrenz, Agata Wilk, Marina Chepeleva, Oliver Mücke, Maximilian Schönung, Franziska Petermann, Philipp Kensche, Lena Weiser, Frank Thommen, Gideon Giacomelli, Karl Nordstroem, Edahi Gonzales-Avalos, Angelika Merkel, Helene Kretzmer, Jonas Fischer, Stephen Krämer, Murat Iskar, Stephan Wolf, Ivo Buchhalter, Manel Esteller, Chris Lawerenz, Sven Twardziok, Marc Zapatka, Volker Hovestadt, Matthias Schlesner, Marcel H. Schulz, Steve Hoffmann, Clarissa Gerhäuser, Jörn Walter, Mark Hartmann, Daniel B. Lipka, Yassen Assenov, Christoph Bock, Christoph Plass, Réka Tóth, Pavlo Lutsik (2024). Pipeline Olympics: continuable benchmarking of computational workflows for DNA methylation sequencing data against an experimental gold-standard. , DOI: https://doi.org/10.1101/2024.09.16.609142.
Preprint75 days agoThe International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery
Elı́as Campo, Enrique Carrillo de Santa Pau, Lisa H. Chadwick, Kui Ming Chan, Wei Chen, Tom H. Cheung, Luca Chiapperino, Nam‐Kyong Choi, Ho‐Ryun Chung, Laura Clarke, Joseph M. Connors, Philippe Cronet, John Danesh, Manolis Dermitzakis, Gerard Drewes, Pawel Durek, Stephanie O. M. Dyke, Tomasz Dyląg, Connie J. Eaves, Peter Ebert, Roland Eils, Roland Eils, Catherine Ennis, Tariq Enver, Elise A. Feingold, Bärbel Felder, Anne C. Ferguson‐Smith, Jude Fitzgibbon, Paul Flicek, Roger Foo, Peter Fraser, Mattia Frontini, Eileen E. M. Furlong, Sitanshu Gakkhar, Nina Gasparoni, Gilles Gasparoni, Daniel H. Geschwind, Petar Glažar, Thomas Graf, Frank Grosveld, Xin‐Yuan Guan, Roderic Guigó, Marta Gut, Alf Hamann, Bok-Ghee Han, R. Alan Harris, Simon Heath, Kristian Helin, Jan G. Hengstler, Alireza Heravi‐Moussavi, Karl Herrup, Steven Hill, Jason A. Hilton, Benjamin C. Hitz, Bernhard Horsthemke, Ming Hu, Joo-Yeon Hwang, Nancy Y. Ip, Takashi Ito, Biola M. Javierre, Sasa Jenko, Thomas Jenuwein, Yann Joly, Steven J.M. Jones, Yae Kanai, Hee Gyung Kang, Aly Karsan, Alexandra K. Kiemer, Song Cheol Kim, H.G. Stunnenberg, Martin Hirst, Sergio Abrignani, David J. Adams, Melanie de Almeida, Lucia Altucci, Viren Amin, Ido Amit, Stylianos E. Antonarakis, Samuel Aparício, Takahiro Arima, Laura Arrigoni, Rob J.W. Arts, Vahid Asnafi, Manel Esteller, Jae‐Bum Bae, Kevin Baßler, Stephan Beck, Benjamin E. Berkman, B Bernstein, Mikhail Bilenky, Adrian Bird, Christoph Bock, Bernhard O. Boehm, Guillaume Bourque, Charles E. Breeze, Benedikt Brors, David Bujold, Oliver S. Burren, Marion J.G. Bussemakers, Adam S. Butterworth (2016). The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery. , 167(5), DOI: https://doi.org/10.1016/j.cell.2016.11.007.
Article75 days agoEpigenetic Homogeneity Within Colorectal Tumors Predicts Shorter Relapse-Free and Overall Survival Times for Patients With Locoregional Cancer
Anna Martínez‐Cardús, Sebastián Morán, Eva Musulén, Cátia Moutinho, José Luís Manzano, Eva Martinez‐Balibrea, Montserrat Tierno, Elena Élez, Stefania Landolfi, Patricia Lorden, Carles Arribas, Fabian Müller, Christoph Bock, Josep Tabernero, Manel Esteller (2016). Epigenetic Homogeneity Within Colorectal Tumors Predicts Shorter Relapse-Free and Overall Survival Times for Patients With Locoregional Cancer. , 151(5), DOI: https://doi.org/10.1053/j.gastro.2016.08.001.
Article75 days agoToward understanding and exploiting tumor heterogeneity
Ash A. Alizadeh, Victoria Aranda, Alberto Bardelli, Cédric Blanpain, Christoph Bock, Christine Borowski, Carlos Caldas, Andrea Califano, Michael Doherty, Markus Elsner, Manel Esteller, Rebecca C. Fitzgerald, Jan O. Korbel, Peter Lichter, Christopher E. Mason, Nicholas E. Navin, Dana Pe’er, Kornélia Polyák, Charles W.M. Roberts, Lillian L. Siu, Alexandra Snyder, Hannah Stower, Charles Swanton, Roel G.W. Verhaak, Jean C. Zenklusen, Johannes Zuber, Jessica Zucman‐Rossi (2015). Toward understanding and exploiting tumor heterogeneity. , 21(8), DOI: https://doi.org/10.1038/nm.3915.
Article75 days agoPromoter hypermethylation of the phosphatase DUSP22 mediates PKA‐dependent TAU phosphorylation and CREB activation in Alzheimer's disease
José V. Sánchez‐Mut, Ester Aso, Holger Heyn, Tadashi Matsuda, Christoph Bock, Isidró Ferrer, Manel Esteller (2014). Promoter hypermethylation of the phosphatase DUSP22 mediates PKA‐dependent TAU phosphorylation and CREB activation in Alzheimer's disease. , 24(4), DOI: https://doi.org/10.1002/hipo.22245.
Article75 days ago