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Evidence for a Trade‐Off between Survival and Fitness Caused by Resveratrol Treatment of <i>Caenorhabditis elegans</i>
Jan Gruber, Soon Yew Tang, Barry Halliwell (2007). Evidence for a Trade‐Off between Survival and Fitness Caused by Resveratrol Treatment of <i>Caenorhabditis elegans</i>. Annals of the New York Academy of Sciences, 1100(1), pp. 530-542, DOI: 10.1196/annals.1395.059.
Article148 days agoThe mitochondria-targeted antioxidant MitoQ extends lifespan and improves healthspan of a transgenic Caenorhabditis elegans model of Alzheimer disease
Li Fang Ng, Jan Gruber, Irwin K. Cheah, Chong Kiat Goo, Wei Fun Cheong, Guanghou Shui, Kim Ping Sit, Markus R. Wenk, Barry Halliwell (2014). The mitochondria-targeted antioxidant MitoQ extends lifespan and improves healthspan of a transgenic Caenorhabditis elegans model of Alzheimer disease. Free Radical Biology and Medicine, 71, pp. 390-401, DOI: 10.1016/j.freeradbiomed.2014.03.003.
Article148 days agoDeceptively simple but simply deceptive – <i>Caenorhabditis elegans</i> lifespan studies: Considerations for aging and antioxidant effects
Jan Gruber, Li Fang Ng, Suresh Poovathingal, Barry Halliwell (2009). Deceptively simple but simply deceptive – <i>Caenorhabditis elegans</i> lifespan studies: Considerations for aging and antioxidant effects. FEBS Letters, 583(21), pp. 3377-3387, DOI: 10.1016/j.febslet.2009.09.051.
Article148 days agoMitochondria-targeted antioxidants and metabolic modulators as pharmacological interventions to slow ageing
Jan Gruber, Sheng Fong, Ce-Belle Chen, Sialee Yoong, Giorgia Pastorin, Sebastian Schaffer, Irwin K. Cheah, Barry Halliwell (2012). Mitochondria-targeted antioxidants and metabolic modulators as pharmacological interventions to slow ageing. Biotechnology Advances, 31(5), pp. 563-592, DOI: 10.1016/j.biotechadv.2012.09.005.
Article148 days agoEnergy crisis precedes global metabolic failure in a novel Caenorhabditis elegans Alzheimer Disease model
Sheng Fong, Emelyne Teo, Li Fang Ng, Ce-Belle Chen, Lakshmi Narayanan Lakshmanan, Sau Yee Tsoi, Philip K. Moore, Takao Inoue, Barry Halliwell, Jan Gruber (2016). Energy crisis precedes global metabolic failure in a novel Caenorhabditis elegans Alzheimer Disease model. Scientific Reports, 6(1), DOI: 10.1038/srep33781.
Article148 days ago