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The last 5 uploaded publications
Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis
Shahla Abdollahi‐Roodsaz, Leo A. B. Joosten, Marije I. Koenders, Isabel Devesa, Mieke F. Roelofs, Timothy R. D. J. Radstake, Marleen Heuvelmans‐Jacobs, Akira Shizuo, Martin J.H. Nicklin, Fátima Ribeiro‐Dias, Wim B. van den Berg (2008). Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis. Journal of Clinical Investigation, 118(1), pp. 205-216, DOI: 10.1172/jci32639.
Article179 days agoDeficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance
Mihai G. Netea, Leo A. B. Joosten, Eli C. Lewis, Dalan R. Jensen, Peter J. Voshol, Bart Jan Kullberg, Cees J. Tack, J. Han van Krieken, Soohyun Kim, Anton F. H. Stalenhoef, F.A. van de Loo, Ineke Verschueren, Leslie K. Pulawa, Akira Shizuo, Robert H. Eckel, Charles A. Dinarello, W. van den Berg, Jos W.M. van der Meer (2006). Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance. Nature Medicine, 12(6), pp. 650-656, DOI: 10.1038/nm1415.
Article179 days agoToll-Like Receptor 2 Pathway Drives Streptococcal Cell Wall-Induced Joint Inflammation: Critical Role of Myeloid Differentiation Factor 88
Leo A. B. Joosten, Marije I. Koenders, Ruben L. Smeets, Marleen Heuvelmans‐Jacobs, Monique M. Helsen, Kiyoshi Takeda, Akira Shizuo, Erik Lubberts, Fons A. J. van de Loo, Wim B. van den Berg (2003). Toll-Like Receptor 2 Pathway Drives Streptococcal Cell Wall-Induced Joint Inflammation: Critical Role of Myeloid Differentiation Factor 88. The Journal of Immunology, 171(11), pp. 6145-6153, DOI: 10.4049/jimmunol.171.11.6145.
Article174 days agoTrained immunity: A program of innate immune memory in health and disease
Mihai G. Netea, Leo A. B. Joosten, Eicke Latz, Kingston H. G. Mills, Gioacchino Natoli, Hendrik G. Stunnenberg, Luke O'neill, Ramnik J. Xavier (2016). Trained immunity: A program of innate immune memory in health and disease. Science, 352(6284), DOI: 10.1126/science.aaf1098.
Article168 days agomTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity
Shih‐Chin Cheng, Jessica Quintin, Robert A. Cramer, Kelly M. Shepardson, Sadia Saeed, Vinod Kumar, Evangelos J. Giamarellos‐Bourboulis, Joost H.A. Martens, Nagesha Rao, Ali Aghajanirefah, Ganesh R. Manjeri, Li Yang, Daniela C. Ifrim, Rob J.W. Arts, Brian M. J. W. van der Veer, Peter M.T. Deen, Colin Logie, Luke O'neill, Peter H.G.M. Willems, Frank L. van de Veerdonk, J.W.M. van der Meer, Aylwin Ng, Leo A. B. Joosten, Cisca Wijmenga, Hendrik G. Stunnenberg, Ramnik J. Xavier, Mihai G. Netea (2014). mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity. Science, 345(6204), DOI: 10.1126/science.1250684.
Article168 days ago