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A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases
Rebecca C. Coll, Avril A. B. Robertson, Jae Jin Chae, Sarah Higgins, Raúl Muñoz-Planillo, Marco Inserra, Irina Vetter, Lara S. Dungan, Brian G. Monks, Andrea Stutz, Daniel E. Croker, Mark S. Butler, Moritz Haneklaus, Caroline E. Sutton, Gabriel Núñez, Eicke Latz, Daniel L. Kastner, Kingston H. G. Mills, Seth L. Masters, Kate Schroder, Matthew A. Cooper, Luke O'neill (2015). A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases. Nature Medicine, 21(3), pp. 248-255, DOI: 10.1038/nm.3806.
Article167 days ago30: MCC950 is a potent and specific inhibitor of the NLRP3 inflammasome and a novel potential therapeutic for NLRP3 driven diseases
Rebecca C. Coll, Avril A. B. Robertson, Jae Jin Chae, Sarah Higgins, Lara S. Dungan, Raúl Muñoz-Planillo, Brian G. Monks, Daniel E. Croker, Caroline E. Sutton, Andrea Stutz, Gabriel Núñez, Eicke Latz, Daniel L. Kastner, Kingston H. G. Mills, Seth L. Masters, Kate Schroder, Matt A. Cooper, Luke O'neill (2014). 30: MCC950 is a potent and specific inhibitor of the NLRP3 inflammasome and a novel potential therapeutic for NLRP3 driven diseases. Cytokine, 70(1), pp. 35-35, DOI: 10.1016/j.cyto.2014.07.037.
Article167 days ago