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The last 5 uploaded publications
Klotho expression is reduced in COPD airway epithelial cells: effects on inflammation and oxidant injury
Wei Gao, Cheng Yuan, Jingying Zhang, Ling‐Ling Li, Li Yu, Coen Wiegman, Peter J Barnes, Ian M. Adcock, Mao Huang, Xin Yao (2015). Klotho expression is reduced in COPD airway epithelial cells: effects on inflammation and oxidant injury. , 129(12), DOI: https://doi.org/10.1042/cs20150273.
Article54 days agoOxidative stress–induced mitochondrial dysfunction drives inflammation and airway smooth muscle remodeling in patients with chronic obstructive pulmonary disease
Coen Wiegman, Charalambos Michaeloudes, Gulammehdi Haji, Priyanka Narang, Colin Clarke, Kirsty Russell, Wuping Bao, Stelios Pavlidis, Peter J Barnes, Justin Kanerva, Anton Bittner, Navin Rao, Michael P. Murphy, Paul Kirkham, Kian Fan Chung, Ian M. Adcock, Christopher E. Brightling, Donna E. Davies, Donna K. Finch, Andrew J. Fisher, A. Gaw, Alan J. Knox, Ruth J. Mayer, Michael I. Polkey, Michael Salmon, David Singh (2015). Oxidative stress–induced mitochondrial dysfunction drives inflammation and airway smooth muscle remodeling in patients with chronic obstructive pulmonary disease. , 136(3), DOI: https://doi.org/10.1016/j.jaci.2015.01.046.
Article54 days agoHypoxia Inducible Factor-1α binding to HDAC2 and MIF promoter regions is associated with changes in gene expression levels in chronic ozone exposed mice
Coen Wiegman, Kirsty Russell, Colin Clarke, Peter J Barnes, Ian M. Adcock (2011). Hypoxia Inducible Factor-1α binding to HDAC2 and MIF promoter regions is associated with changes in gene expression levels in chronic ozone exposed mice. , 38
Article54 days agoEffect Of Short-term (3 Day) Cigarette Smoke-exposure In Mice On Histone Deacetylase (HDAC)2 And Hypoxia Inducible Factor (HIF)-1± Function
Coen Wiegman, Nicolas O.J. Moriceau, Mark J. Paul‐Clark, Jane A. Mitchell, Ian M. Adcock, Peter J Barnes (2010). Effect Of Short-term (3 Day) Cigarette Smoke-exposure In Mice On Histone Deacetylase (HDAC)2 And Hypoxia Inducible Factor (HIF)-1± Function. , DOI: https://doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a2914.
Article54 days agoThe MIF Antagonist ISO-1 Attenuates Corticosteroid-Insensitive Inflammation and Airways Hyperresponsiveness in an Ozone-Induced Model of COPD
Kirsty Russell, Kian Fan Chung, Colin Clarke, Andrew Durham, Patrick Mallia, Joseph Footitt, Sebastian L. Johnston, Peter J Barnes, Simon R. Hall, Karen D. Simpson, Malcolm R. Starkey, Philip M. Hansbro, Ian M. Adcock, Coen Wiegman (2016). The MIF Antagonist ISO-1 Attenuates Corticosteroid-Insensitive Inflammation and Airways Hyperresponsiveness in an Ozone-Induced Model of COPD. , 11(1), DOI: https://doi.org/10.1371/journal.pone.0146102.
Article54 days ago