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Inhibition of Gsk3b Reduces Nfkb1 Signaling and Rescues Synaptic Activity to Improve the Rett Syndrome Phenotype in Mecp2-Knockout Mice
Olga C. Jorge-Torres, Karolina Szczęsna, Laura M. Roa, Carmen Casal, Louisa González Somermeyer, Marta Soler, Cecilia D. Velasco, Pablo Martínez San Segundo, Paolo Petazzi, Mauricio A. Sáez, Raúl Delgado‐Morales, Stéphane Fourcade, Aurora Pujol, Dori Huertas, Artur Llobet, Sònia Guil, Manel Esteller (2018). Inhibition of Gsk3b Reduces Nfkb1 Signaling and Rescues Synaptic Activity to Improve the Rett Syndrome Phenotype in Mecp2-Knockout Mice. , 23(6), DOI: https://doi.org/10.1016/j.celrep.2018.04.010.
Article74 days agoInhibition of Gsk3b Reduces Nfkb1 Signaling and Rescues Synaptic Activity to Improve the Rett Syndrome Phenotype in Mecp2-Knockout Mice
Olga C. Jorge-Torres, Karolina Szczęsna, Laura M. Roa, Carmen Casal, Louisa González Somermeyer, Marta Soler, Cecilia D. Velasco, Pablo Martínez San Segundo, Paolo Petazzi, Mauricio A. Sáez, Raúl Delgado‐Morales, Stéphane Fourcade, Aurora Pujol, Dori Huertas, Artur Llobet, Sònia Guil, Manel Esteller (2018). Inhibition of Gsk3b Reduces Nfkb1 Signaling and Rescues Synaptic Activity to Improve the Rett Syndrome Phenotype in Mecp2-Knockout Mice. , 23(6), DOI: https://doi.org/10.1016/j.celrep.2018.04.010.
Article74 days agoBromodomain inhibition shows antitumoral activity in mice and human luminal breast cancer
Montserrat Pérez-Salvia, Laia Simó‐Riudalbas, Pere Llinàs‐Arias, Laura M. Roa, Fernando Setién, Marta Soler, Manuel Castro de Moura, James E. Bradner, Eva González‐Suárez, Cátia Moutinho, Manel Esteller (2017). Bromodomain inhibition shows antitumoral activity in mice and human luminal breast cancer. , 8(31), DOI: https://doi.org/10.18632/oncotarget.18255.
Article74 days agoImprovement of the Rett Syndrome Phenotype in a Mecp2 Mouse Model Upon Treatment with Levodopa and a Dopa-Decarboxylase Inhibitor
Karolina Szczęsna, Olga de la Caridad, Paolo Petazzi, Marta Soler, Laura M. Roa, Mauricio A. Sáez, Stéphane Fourcade, Aurora Pujol, Rafael Artuch-Iriberri, Marta Molero‐Luis, August Vidal, Dori Huertas, Manel Esteller (2014). Improvement of the Rett Syndrome Phenotype in a Mecp2 Mouse Model Upon Treatment with Levodopa and a Dopa-Decarboxylase Inhibitor. , 39(12), DOI: https://doi.org/10.1038/npp.2014.136.
Article74 days agoWhole exome sequencing of Rett syndrome-like patients reveals the mutational diversity of the clinical phenotype
Mario Lucariello, Enrique Vidal, Silvia M. Vidal, Mauricio A. Sáez, Laura M. Roa, Dori Huertas, Mercè Pineda, Esther Dalfó, Joaquı́n Dopazo, Paola Jurado, Judith Armstrong, Manel Esteller (2016). Whole exome sequencing of Rett syndrome-like patients reveals the mutational diversity of the clinical phenotype. , 135(12), DOI: https://doi.org/10.1007/s00439-016-1721-3.
Article74 days ago