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The last 5 uploaded publications
Germline missense pathogenic variants in the BRCA1 BRCT domain, p.Gly1706Glu and p.Ala1708Glu, increase cellular sensitivity to PARP inhibitor olaparib by a dominant negative effect
Tereza Vaclová, Nicholas T. Woods, Diego Megı́as, Sergio Gómez-López, Fernando Setién, José María García Bueno, José A. Macías, Alicia Barroso, Miguel Urioste, Manel Esteller, Álvaro N.A. Monteiro, Javier Benı́tez, Ana Osório (2016). Germline missense pathogenic variants in the BRCA1 BRCT domain, p.Gly1706Glu and p.Ala1708Glu, increase cellular sensitivity to PARP inhibitor olaparib by a dominant negative effect. , DOI: https://doi.org/10.1093/hmg/ddw343.
Article75 days agoDNA repair capacity is impaired in healthy BRCA1 heterozygous mutation carriers
Tereza Vaclová, Gonzalo Goméz-López, Fernando Setién, José María García Bueno, José Antonio Macías, Alicia Barroso, Miguel Urioste, Manel Esteller, Javier Benı́tez, Ana Osório (2015). DNA repair capacity is impaired in healthy BRCA1 heterozygous mutation carriers. , 152(2), DOI: https://doi.org/10.1007/s10549-015-3459-3.
Article75 days agoAbstract 5483: Implications of the type of <i>BRCA1</i> germline mutation in the treatment of patients with hereditary breast cancer
Tereza Vaclová, Nicholas T. Woods, Fernando Setién, José María García Bueno, José A. Macías, Alicia Barroso, Miguel Urioste, Manel Esteller, Álvaro N.A. Monteiro, Javier Benı́tez, Ana Osório (2014). Abstract 5483: Implications of the type of <i>BRCA1</i> germline mutation in the treatment of patients with hereditary breast cancer. , 74(19_Supplement), DOI: https://doi.org/10.1158/1538-7445.am2014-5483.
Article75 days ago