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Get Free AccessDue to its many advantages, the nematode worm Caenorhabditis elegans (C. elegans) is commonly employed as a convenient model for aging studies as well as for testing life span effects of chemical compounds. However, some challenges exist in the context of such life span studies, particularly in relation to generation and maintenance of synchronized cohorts, and these challenges are not always fully appreciated. Here we discuss the impact of incomplete control of nematode proliferation on life span studies and suggest some solutions to minimize these artefacts.
Jan Gruber, Suresh Poovathingal, Sebastian Schaffer, Li Fang Ng, Rudiyanto Gunawan, Barry Halliwell (2010). <i>Caenorhabditis elegans</i> Life Span Studies: The Challenge of Maintaining Synchronous Cohorts. , 13(2-3), DOI: https://doi.org/10.1089/rej.2009.0943.
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Type
Article
Year
2010
Authors
6
Datasets
0
Total Files
0
Language
en
DOI
https://doi.org/10.1089/rej.2009.0943
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