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The last 5 uploaded publications
Enantioselective Synthesis of Spirocyclic Nitrogen-Containing Heterocycles Catalyzed by an Iridium-Containing Cytochrome
Jingtong Xu, Brandon J. Bloomer, John N. Brunn, Andrew P. Quest, Sukriyo Chakraborty, Joseph E. Schneider, Douglas S. Clark, John F Hartwig (2025). Enantioselective Synthesis of Spirocyclic Nitrogen-Containing Heterocycles Catalyzed by an Iridium-Containing Cytochrome. , 147(32), DOI: https://doi.org/10.1021/jacs.5c06239.
Article110 days agoEnantio- and Diastereodivergent Cyclopropanation of Allenes by Directed Evolution of an Iridium-Containing Cytochrome
Brandon J. Bloomer, Isaac A. Joyner, Marc Garcia‐Borràs, Derek B. Hu, Martí Garçon, Andrew F. G. Quest, Consuelo Ugarte Montero, Isaac Furay Yu, Douglas S. Clark, John F Hartwig (2024). Enantio- and Diastereodivergent Cyclopropanation of Allenes by Directed Evolution of an Iridium-Containing Cytochrome. , 146(3), DOI: https://doi.org/10.1021/jacs.3c13011.
Article110 days agoA Chemoenzymatic Hydroaminomethylation Strategy for the Selective Synthesis of Linear Primary Amines from Olefins by Sequential and Tandem Processes
Jenna L. Manske, Jeremy Nicolai, Brandon J. Bloomer, Douglas S. Clark, John F Hartwig (2024). A Chemoenzymatic Hydroaminomethylation Strategy for the Selective Synthesis of Linear Primary Amines from Olefins by Sequential and Tandem Processes. , 14(19), DOI: https://doi.org/10.1021/acscatal.4c03770.
Article110 days agoCCDC 2309994: Experimental Crystal Structure Determination
Brandon J. Bloomer, Isaac A. Joyner, Marc Garcia‐Borràs, Derek B. Hu, Martí Garçon, Andrew F. G. Quest, Consuelo Ugarte Montero, Isaac Furay Yu, Douglas S. Clark, John F HartwigCCDC 2309994: Experimental Crystal Structure Determination. , DOI: https://doi.org/10.5517/ccdc.csd.cc2hjqyq.
Dataset110 days agoMechanistic and structural characterization of an iridium-containing cytochrome reveals kinetically relevant cofactor dynamics
Brandon J. Bloomer, Sean N. Natoli, Marc Garcia‐Borràs, J.H. Pereira, Derek B. Hu, Paul D. Adams, K. N. Houk, Douglas S. Clark, John F Hartwig (2023). Mechanistic and structural characterization of an iridium-containing cytochrome reveals kinetically relevant cofactor dynamics. , 6(1), DOI: https://doi.org/10.1038/s41929-022-00899-9.
Article110 days ago