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Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages
Eva M. Pålsson‐McDermott, Annie M. Curtis, Gautam Goel, Mario A. Lauterbach, Frederick J. Sheedy, Laura E. Gleeson, Mirjam W.M. van den Bosch, Susan R. Quinn, Raquel Domingo-Fernandéz, Daniel Johnston, Jian‐kang Jiang, William J. Israelsen, Joseph Keane, Craig J. Thomas, Clary B. Clish, Matthew G. Vander Heiden, Ramnik J. Xavier, Luke O'neill (2015). Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages. Cell Metabolism, 21(1), pp. 65-80, DOI: 10.1016/j.cmet.2014.12.005.
Article167 days agoLoss of MicroRNA-21 Influences the Gut Microbiota, Causing Reduced Susceptibility in a Murine Model of Colitis
Daniel Johnston, Michelle A. Williams, Christoph A. Thaiss, Raúl Cabrera‐Rubio, Mathilde Raverdeau, Craig P. McEntee, Paul D. Cotter, Eran Elinav, Luke O'neill, Sinéad C. Corr (2018). Loss of MicroRNA-21 Influences the Gut Microbiota, Causing Reduced Susceptibility in a Murine Model of Colitis. Journal of Crohn s and Colitis, 12(7), pp. 835-848, DOI: 10.1093/ecco-jcc/jjy038.
Article167 days agoMicroRNA-21 Limits Uptake of Listeria monocytogenes by Macrophages to Reduce the Intracellular Niche and Control Infection
Daniel Johnston, Jay Kearney, Zbigniew Zasłona, Michelle A. Williams, Luke O'neill, Sinéad C. Corr (2017). MicroRNA-21 Limits Uptake of Listeria monocytogenes by Macrophages to Reduce the Intracellular Niche and Control Infection. Frontiers in Cellular and Infection Microbiology, 7, DOI: 10.3389/fcimb.2017.00201.
Article167 days agoMyD88 adaptor-like (Mal) regulates intestinal homeostasis and colitis-associated colorectal cancer in mice
Gabriella Aviello, Sinéad C. Corr, Daniel Johnston, Luke O'neill, Padraic G. Fallon (2014). MyD88 adaptor-like (Mal) regulates intestinal homeostasis and colitis-associated colorectal cancer in mice. AJP Gastrointestinal and Liver Physiology, 306(9), pp. G769-G778, DOI: 10.1152/ajpgi.00399.2013.
Article167 days agoSu1893 Modulation of Intestinal Homeostasis and Microbial Activities by miR-21 in the Pathogenesis of Inflammatory Bowel Disease
Daniel Johnston, Luke O'neill, Sinéad C. Corr (2016). Su1893 Modulation of Intestinal Homeostasis and Microbial Activities by miR-21 in the Pathogenesis of Inflammatory Bowel Disease. Gastroenterology, 150(4), pp. S581-S581, DOI: 10.1016/s0016-5085(16)31992-8.
Article167 days ago