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The last 5 uploaded publications
Dimethyl fumarate and 4-octyl itaconate are anticoagulants that suppress Tissue Factor in macrophages via inhibition of Type I Interferon
Tristram A. J. Ryan, Alexander Hooftman, Aisling M. Rehill, Matt D. Johansen, Eóin C. O’ Brien, Juliana E. Toller-Kawahisa, Mieszko M. Wilk, Emily A. Day, Hauke J. Weiss, Pourya Sarvari, Emilio G. Vozza, Fabian Schramm, Christian G. Peace, Alessia Zotta, Stefan Miemczyk, Christina Nalkurthi, Nicole G. Hansbro, Gavin McManus, Laura O’Doherty, Siobhán Gargan, Aideen Long, Jean Dunne, Clíona Ní Cheallaigh, Niall Conlon, Michael Carty, Padraic G. Fallon, Kingston H. G. Mills, Emma M. Creagh, James S. O’ Donnell, Paul J. Hertzog, Philip M. Hansbro, Rachel M. McLoughlin, Małgorzata Wygrecka, Roger J. S. Preston, Zbigniew Zasłona, Luke O'neill (2023). Dimethyl fumarate and 4-octyl itaconate are anticoagulants that suppress Tissue Factor in macrophages via inhibition of Type I Interferon. Nature Communications, 14(1), DOI: 10.1038/s41467-023-39174-1.
Article167 days agoTrained immunity causes myeloid cell hypercoagulability
Aisling M. Rehill, Seán McCluskey, Anna E. Ledwith, Tristram A. J. Ryan, Betül Ünlü, Gemma Leon, Hugo Charles‐Messance, Edmund Gilbert, Paula Klavina, Emily A. Day, Judith A. Coppinger, Jamie M. O’Sullivan, Corrina McMahon, James S. O’Donnell, Annie M. Curtis, Luke O'neill, Frederick J. Sheedy, Roger J. S. Preston (2025). Trained immunity causes myeloid cell hypercoagulability. Science Advances, 11(10), DOI: 10.1126/sciadv.ads0105.
Article167 days agoTrained Immunity Causes Myeloid Cell Hypercoagulability
Aisling M. Rehill, Seán McCluskey, Anna E. Ledwith, Tristram A. J. Ryan, Gemma Leon, Hugo Charles‐Messance, Edmund Gilbert, Emily A. Day, Corrina McMahon, James S. O’Donnell, Annie M. Curtis, Luke O'neill, Frederick J. Sheedy, Roger J. S. Preston (2024). Trained Immunity Causes Myeloid Cell Hypercoagulability. bioRxiv (Cold Spring Harbor Laboratory), DOI: 10.1101/2024.07.16.603679.
Preprint167 days agoOC 55.2 Dimethyl Fumarate and 4-Octyl Itaconate are Anticoagulants that Suppress Tissue Factor in Macrophages Via Inhibition of Type I Interferon
T.J. RYAN, Alexander Hooftman, Aisling M. Rehill, Mary Johansen, Eoin O’Brien, Juliana E. Toller-Kawahisa, Eric S. Day, Harvey R. Weiss, C. Peace, Alessia Zotta, Nicole G. Hansbro, James S. O’Donnell, Philip M. Hansbro, Robert J. McLoughlin, Małgorzata Wygrecka, Roger J. S. Preston, Z. Zasłona, Luke O'neill (2023). OC 55.2 Dimethyl Fumarate and 4-Octyl Itaconate are Anticoagulants that Suppress Tissue Factor in Macrophages Via Inhibition of Type I Interferon. Research and Practice in Thrombosis and Haemostasis, 7, pp. 100502-100502, DOI: 10.1016/j.rpth.2023.100502.
Article167 days agoOC 55.2 Dimethyl Fumarate and 4-Octyl Itaconate are Anticoagulants that Suppress Tissue Factor in Macrophages Via Inhibition of Type I Interferon
T.J. RYAN, Alexander Hooftman, Aisling M. Rehill, Mary Johansen, Eoin O’Brien, Juliana E. Toller-Kawahisa, Eric S. Day, Harvey R. Weiss, C. Peace, Alessia Zotta, Nicole G. Hansbro, James S. O’Donnell, Philip M. Hansbro, Robert J. McLoughlin, Małgorzata Wygrecka, Roger J. S. Preston, Z. Zasłona, Luke O'neill (2023). OC 55.2 Dimethyl Fumarate and 4-Octyl Itaconate are Anticoagulants that Suppress Tissue Factor in Macrophages Via Inhibition of Type I Interferon. Research and Practice in Thrombosis and Haemostasis, 7, pp. 100502-100502, DOI: 10.1016/j.rpth.2023.100502.
Article144 days ago