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The last 5 uploaded publications
The intracellular chloride channel proteins CLIC1 and CLIC4 induce IL-1β transcription and activate the NLRP3 inflammasome
Raquel Domingo-Fernandéz, Rebecca C. Coll, Jay Kearney, Samuel N. Breit, Luke O'neill (2017). The intracellular chloride channel proteins CLIC1 and CLIC4 induce IL-1β transcription and activate the NLRP3 inflammasome. Journal of Biological Chemistry, 292(29), pp. 12077-12087, DOI: 10.1074/jbc.m117.797126.
Article167 days agoCaspase-11 promotes allergic airway inflammation
Zbigniew Zasłona, Ewelina Flis, Mieszko M. Wilk, Richard G. Carroll, Eva M. Pålsson‐McDermott, Mark Hughes, Ciana Diskin, Kathy Banahan, Dylan G. Ryan, Alexander Hooftman, Alicja Misiak, Jay Kearney, Günter Lochnit, Wilhelm Bertrams, Timm Greulich, Bernd Schmeck, Oliver J. McElvaney, Kingston H. G. Mills, Ed C. Lavelle, Małgorzata Wygrecka, Emma M. Creagh, Luke O'neill (2020). Caspase-11 promotes allergic airway inflammation. Nature Communications, 11(1), DOI: 10.1038/s41467-020-14945-2.
Article167 days agoMicroRNA-21 Limits Uptake of Listeria monocytogenes by Macrophages to Reduce the Intracellular Niche and Control Infection
Daniel Johnston, Jay Kearney, Zbigniew Zasłona, Michelle A. Williams, Luke O'neill, Sinéad C. Corr (2017). MicroRNA-21 Limits Uptake of Listeria monocytogenes by Macrophages to Reduce the Intracellular Niche and Control Infection. Frontiers in Cellular and Infection Microbiology, 7, DOI: 10.3389/fcimb.2017.00201.
Article167 days agoCaspase-4: A Therapeutic Target for Peptic Ulcer Disease
Zbigniew Zasłona, Ewelina Flis, Ciara Nulty, Jay Kearney, Rebecca Fitzgerald, Atiyekeogbebe Rita Douglas, Deirdre McNamara, Sinead Smith, Luke O'neill, Emma M. Creagh (2020). Caspase-4: A Therapeutic Target for Peptic Ulcer Disease. ImmunoHorizons, 4(10), pp. 627-633, DOI: 10.4049/immunohorizons.2000080.
Article167 days ago