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The last 5 uploaded publications
Modification of Proteins by Metabolites in Immunity
Ciana Diskin, Tristram A. J. Ryan, Luke O'neill (2020). Modification of Proteins by Metabolites in Immunity. Immunity, 54(1), pp. 19-31, DOI: 10.1016/j.immuni.2020.09.014.
Article167 days agoCaspase-11 promotes allergic airway inflammation
Zbigniew Zasłona, Ewelina Flis, Mieszko M. Wilk, Richard G. Carroll, Eva M. Pålsson‐McDermott, Mark Hughes, Ciana Diskin, Kathy Banahan, Dylan G. Ryan, Alexander Hooftman, Alicja Misiak, Jay Kearney, Günter Lochnit, Wilhelm Bertrams, Timm Greulich, Bernd Schmeck, Oliver J. McElvaney, Kingston H. G. Mills, Ed C. Lavelle, Małgorzata Wygrecka, Emma M. Creagh, Luke O'neill (2020). Caspase-11 promotes allergic airway inflammation. Nature Communications, 11(1), DOI: 10.1038/s41467-020-14945-2.
Article167 days agoGlutathione Transferase Omega-1 Regulates NLRP3 Inflammasome Activation through NEK7 Deglutathionylation
Mark Hughes, Alexander Hooftman, Stefano Angiari, Padmaja Tummala, Zbigniew Zasłona, Marah C. Runtsch, Anne F. McGettrick, Caroline E. Sutton, Ciana Diskin, Melissa Rooke, Shuhei Takahashi, Srinivasan Sundararaj, Marco G. Casarotto, Jane E. Dahlstrom, Eva M. Pålsson‐McDermott, Sinéad C. Corr, Kingston H. G. Mills, Roger J. S. Preston, Nouri Neamati, Yiyue Xie, Jonathan B. Baell, Philip G. Board, Luke O'neill (2019). Glutathione Transferase Omega-1 Regulates NLRP3 Inflammasome Activation through NEK7 Deglutathionylation. Cell Reports, 29(1), pp. 151-161.e5, DOI: 10.1016/j.celrep.2019.08.072.
Article167 days ago4-Octyl-Itaconate and Dimethyl Fumarate Inhibit COX2 Expression and Prostaglandin Production in Macrophages
Ciana Diskin, Alessia Zotta, Sarah E. Corcoran, Victoria J. Tyrrell, Zbigniew Zasłona, Valerie B. O’Donnell, Luke O'neill (2021). 4-Octyl-Itaconate and Dimethyl Fumarate Inhibit COX2 Expression and Prostaglandin Production in Macrophages. The Journal of Immunology, 207(10), pp. 2561-2569, DOI: 10.4049/jimmunol.2100488.
Article167 days agoThe Trypanosome-Derived Metabolite Indole-3-Pyruvate Inhibits Prostaglandin Production in Macrophages by Targeting COX2
Ciana Diskin, Sarah E. Corcoran, Victoria J. Tyrrell, Anne F. McGettrick, Zbigniew Zasłona, Valerie B. O’Donnell, Derek P. Nolan, Luke O'neill (2021). The Trypanosome-Derived Metabolite Indole-3-Pyruvate Inhibits Prostaglandin Production in Macrophages by Targeting COX2. The Journal of Immunology, 207(10), pp. 2551-2560, DOI: 10.4049/jimmunol.2100402.
Article167 days ago