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The last 5 uploaded publications
Epigenetic repression of ROR2 has a Wnt-mediated, pro-tumourigenic role in colon cancer
Ester Lara, Vincenzo Calvanese, Covadonga Huidobro, Agustín F. Fernández, Ángela Moncada-Pazos, Álvaro J. Obaya, Óscar Aguilera, José Manuel González‐Sancho, Laura Sánchez-Sánchez, Aurora Astudillo, Alberto Múñoz, Carlos López-Otı́n, Manel Esteller, Mario F. Fraga (2010). Epigenetic repression of ROR2 has a Wnt-mediated, pro-tumourigenic role in colon cancer. , 9(1), DOI: https://doi.org/10.1186/1476-4598-9-170.
Article74 days agoThe<i>ADAMTS12</i>metalloprotease gene is epigenetically silenced in tumor cells and transcriptionally activated in the stroma during progression of colon cancer
Ángela Moncada-Pazos, Álvaro J. Obaya, Mario F. Fraga, Cristina G. Viloria, Gabriel Capellà, Mireia Gausachs, Manel Esteller, Carlos López-Otı́n, Santiago Cal (2009). The<i>ADAMTS12</i>metalloprotease gene is epigenetically silenced in tumor cells and transcriptionally activated in the stroma during progression of colon cancer. , 122(16), DOI: https://doi.org/10.1242/jcs.050468.
Article74 days agoFrom geroscience to precision geromedicine: Understanding and managing aging
Guido Guido Kroemer, Andrea B. Maier, Ana María Cuervo, Vadim N. Gladyshev, Luigi Ferrucci, Vera Gorbunova, Brian K. Kennedy, Thomas A. Rando, Andrei Seluanov, Felipe Sierra, Eric Verdin, Carlos López-Otı́n (2025). From geroscience to precision geromedicine: Understanding and managing aging. , 188(8), DOI: https://doi.org/10.1016/j.cell.2025.03.011.
Article73 days agoThe vocabulary of geromedicine: gerovocabulary
Guido Guido Kroemer, Carlos López-Otı́n, Andrea B. Maier (2025). The vocabulary of geromedicine: gerovocabulary. , DOI: https://doi.org/10.70401/geromedicine.2025.0002.
Article73 days agoAcyl-CoA-binding protein as a driver of pathological aging
Léa Montégut, Flavia Lambertucci, Lucas Moledo-Nodar, Carmen Fiuza‐Luces, Carlos Rodríguez-López, José Antonio Serra Rexach, Sylvie Lachkar, Omar Motiño, Mahmoud Abdellatif, Sylvère Durand, Fanny Aprahamian, Vincent Carbonnier, Delphine Le Corre, Sophie Mouillet‐Richard, Hui Chen, Allan Sauvat, Yanbing Dong, S N Li, Rong Yan, Federico Pietrocola, Pierre Laurent‐Puig, Carlos López-Otı́n, Isabelle Martins, Clea Bárcena, Alejandro Lucı́a, Guido Guido Kroemer (2025). Acyl-CoA-binding protein as a driver of pathological aging. , 122(28), DOI: https://doi.org/10.1073/pnas.2501584122.
Article73 days ago