Loading publications…
The last 5 uploaded publications
5'-Triphosphate RNA Is the Ligand for RIG-I
Veit Hornung, Jana M. Ellegast, Sarah Kim-Hellmuth, Krzysztof Brzózka, Andreas Jung, Hiroki Kato, Hendrik Poeck, Akira Shizuo, Karl‐Klaus Conzelmann, Martin Schlee, Stefan Endres, Gunther Hartmann (2006). 5'-Triphosphate RNA Is the Ligand for RIG-I. Science, 314(5801), pp. 994-997, DOI: 10.1126/science.1132505.
Article184 days agoSequence-specific potent induction of IFN-α by short interfering RNA in plasmacytoid dendritic cells through TLR7
Veit Hornung, Margit Guenthner‐Biller, Carole Bourquin, Andrea Ablasser, Martin Schlee, Satoshi Uematsu, Anne M. Noronha, Muthiah Manoharan, Akira Shizuo, Antonin de Fougerolles, Stefan Endres, Gunther Hartmann (2005). Sequence-specific potent induction of IFN-α by short interfering RNA in plasmacytoid dendritic cells through TLR7. Nature Medicine, 11(3), pp. 263-270, DOI: 10.1038/nm1191.
Article184 days agoRecognition of 5′ Triphosphate by RIG-I Helicase Requires Short Blunt Double-Stranded RNA as Contained in Panhandle of Negative-Strand Virus
Martin Schlee, Andreas Roth, Veit Hornung, Cristina Amparo Hagmann, Vera Wimmenauer, Winfried Barchet, Christoph Coch, Markus Janke, Aleksandra Mihailović, Greg Wardle, Stefan Juranek, Hiroki Kato, Taro Kawai, Hendrik Poeck, Katherine A. Fitzgerald, Osamu Takeuchi, Akira Shizuo, Thomas Tuschl, Eicke Latz, János Ludwig, Gunther Hartmann (2009). Recognition of 5′ Triphosphate by RIG-I Helicase Requires Short Blunt Double-Stranded RNA as Contained in Panhandle of Negative-Strand Virus. Immunity, 31(1), pp. 25-34, DOI: 10.1016/j.immuni.2009.05.008.
Article178 days agoRecognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1β production
Hendrik Poeck, Michael Bscheider, Olaf Groß, Katrin Finger, Susanne Roth, Manuele Rebsamen, Nicole Hannesschläger, Martin Schlee, Simon Rothenfußer, Winfried Barchet, Hiroki Kato, Akira Shizuo, Satoshi Inoue, Stefan Endres, Christian Peschel, Gunther Hartmann, Veit Hornung, Jürgen Ruland (2009). Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1β production. Nature Immunology, 11(1), pp. 63-69, DOI: 10.1038/ni.1824.
Article178 days ago5′-triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma
Hendrik Poeck, Robert Besch, Cornelius Maihoefer, Marcel Renn, Damiá Tormo, Svetlana Shulga Morskaya, Susanne Kirschnek, Evelyn Gaffal, Jennifer Landsberg, Johannes C. Hellmuth, Andreas Schmidt, David Anz, Michael Bscheider, Tobias Schwerd, Carola Berking, Carole Bourquin, Ulrich Kalinke, Elisabeth Kremmer, Hiroki Kato, Akira Shizuo, Rachel Meyers, Georg Häcker, Michael Neuenhahn, Dirk H. Busch, Jürgen Ruland, Simon Rothenfußer, Marco Prinz, Veit Hornung, Stefan Endres, Thomas Tüting, Gunther Hartmann (2008). 5′-triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma. Nature Medicine, 14(11), pp. 1256-1263, DOI: 10.1038/nm.1887.
Article178 days ago