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The last 5 uploaded publications
Author Reply to Peer Reviews of Targeting the ER stress sensor IRE1 protects the liver from fibrosis through the downregulation of the proteostasis factor P4HB/PDIA1
Younis Hazari, Hery Urra, Valeria A. Garcia Lopez, Lama Habbouche, Javier Diaz, Giovanni Tamburini, Mateus Milani, Philippe Pihán, Sylvère Durand, Fanny Aprahamian, Reese Baxter, Menghao Huang, Xiulin Dong, Helena Vihinen, Ana Batista Gonzalez, Patrício Godoy, Alfredo Criollo, Vlad Ratziu, Fabienne Foufelle, Jan G. Hengstler, Eija Jokitalo, Jessica L. Maiers, Lars Plate, Guido Guido Kroemer, Béatrice Bailly-Maître, Claudio Hetz (2024). Author Reply to Peer Reviews of Targeting the ER stress sensor IRE1 protects the liver from fibrosis through the downregulation of the proteostasis factor P4HB/PDIA1. , DOI: https://doi.org/10.15252/rc.2024283700.
Preprint73 days agoControl of lysosomal-mediated cell death by the pH-dependent calcium channel RECS1
Philippe Pihán, Fernanda Lisbona, Janina Borgonovo, Sandra Edwards‐Jorquera, Paula Nunes, Karen Castillo, Oliver Kepp, Hery Urra, Suvi Saarnio, Helena Vihinen, Amado Carreras‐Sureda, Sabrina Forveille, Allan Sauvat, Daniela De Giorgis, Amaury Pupo, Diego A. Rodríguez, Giovanni Quarato, Alfredo Sagredo, Fernanda Lourido, Anthony Letai, Ramón Latorre, Guido Guido Kroemer, Nicolas Demaurex, Eija Jokitalo, Miguel L. Concha, Álvaro Glavic, Douglas R. Green, Claudio Hetz (2021). Control of lysosomal-mediated cell death by the pH-dependent calcium channel RECS1. , 7(46), DOI: https://doi.org/10.1126/sciadv.abe5469.
Article73 days agoControl of lysosomal-mediated cell death by the pH-dependent calcium channel RECS1
Philippe Pihán, Fernanda Lisbona, Janina Borgonovo, Sandra Edwards‐Jorquera, Paula Nunes, Karen Castillo, Oliver Kepp, Hery Urra, Suvi Saarnio, Helena Vihinen, Amado Carreras‐Sureda, Sabrina Forveille, Allan Sauvat, Daniela De Giorgis, Amaury Pupo, Diego A. Rodríguez, Giovanni Quarato, Alfredo Sagredo, Fernanda Lourido, Anthony Letai, Ramón Latorre, Guido Guido Kroemer, Nicolas Demaurex, Eija Jokitalo, Miguel L. Concha, Álvaro Glavic, Douglas R. Green, Claudio Hetz (2021). Control of lysosomal-mediated cell death by the pH-dependent calcium channel RECS1. , 7(46), DOI: https://doi.org/10.1126/sciadv.abe5469.
Article73 days agoGenotoxic stress triggers the activation of IRE1α-dependent RNA decay to modulate the DNA damage response
Estefanie Dufey, José Manuel Bravo‐San Pedro, Cristián Eggers, Matías González-Quiroz, Hery Urra, Alfredo Sagredo, Denisse Sepúlveda, Philippe Pihán, Amado Carreras-Sureda, Younis Hazari, Eduardo A. Sagredo, Daniela Gutiérrez, Cristian Valls, Alexandra Papaioannou, Diego Acosta‐Alvear, Gisela Campos, Pedro Domingos, Rémy Pedeux, Éric Chevet, Alejandra Álvarez, Patrício Godoy, Peter Walter, Álvaro Glavic, Guido Guido Kroemer, Claudio Hetz (2020). Genotoxic stress triggers the activation of IRE1α-dependent RNA decay to modulate the DNA damage response. , 11(1), DOI: https://doi.org/10.1038/s41467-020-15694-y.
Article73 days agoNon-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics
Amado Carreras‐Sureda, Fabián Jaña, Hery Urra, Sylvère Durand, D.E. Mortenson, Alfredo Sagredo, Galdo Bustos, Younis Hazari, Eva Ramos‐Fernández, Maria Livia Sassano, Philippe Pihán, Alexander R. van Vliet, Matías González-Quiroz, Angie K. Torres, Cheril Tapia‐Rojas, Martijn Kerkhofs, Rubén Vicente, Randal J. Kaufman, Nibaldo C. Inestrosa, Christian González‐Billault, R. Luke Wiseman, Patrizia Agostinis, Geert Bultynck, Felipe A. Court, Guido Guido Kroemer, César Cárdenas, Claudio Hetz (2019). Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics. , 21(6), DOI: https://doi.org/10.1038/s41556-019-0329-y.
Article73 days ago