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The last 5 uploaded publications
Regulation of PRMT5–MDM4 axis is critical in the response to CDK4/6 inhibitors in melanoma
Shatha AbuHammad, Carleen Cullinane, Claire Martin, Zoe Bacolas, Teresa Ward, Huiqin Chen, Alison Slater, Kerry Ardley, Laura Kirby, Keefe T. Chan, Natalie Brajanovski, Lorey Smith, Aparna D. Rao, Emily J. Lelliott, Margarete Kleinschmidt, Ismael A. Vergara, Anthony T. Papenfuss, Peter K. H. Lau, Prerana Ghosh, Sue Haupt, Ygal Haupt, Elaine Sanij, Gretchen Poortinga, Richard B. Pearson, Hendrik Falk, David J. Curtis, Paul A. Stupple, Mark Devlin, Ian P. Street, Michael A. Davies, Grant A. McArthur, Karen E. Sheppard (2019). Regulation of PRMT5–MDM4 axis is critical in the response to CDK4/6 inhibitors in melanoma. , 116(36), DOI: https://doi.org/10.1073/pnas.1901323116.
Article62 days agoPalbociclib synergizes with BRAF and MEK inhibitors in treatment naïve melanoma but not after the development of BRAF inhibitor resistance
Claire Martin, Carleen Cullinane, Laura Kirby, Shatha AbuHammad, Emily J. Lelliott, Kelly Waldeck, Richard J. Young, Natalie Brajanovski, Donald P. Cameron, Rachael Walker, Elaine Sanij, Gretchen Poortinga, Ross D. Hannan, Richard B. Pearson, Rodney J. Hicks, Grant A. McArthur, Karen E. Sheppard (2017). Palbociclib synergizes with BRAF and MEK inhibitors in treatment naïve melanoma but not after the development of BRAF inhibitor resistance. , 142(10), DOI: https://doi.org/10.1002/ijc.31220.
Article62 days agoAdaptive post-transcriptional reprogramming of metabolism limits response to targeted therapy in BRAF<sup>V600</sup> melanoma
Lorey Smith, Tiffany J. Parmenter, Margarete Kleinschmidt, Eric Kusnadi, Jian Jian Kang, Claire Martin, Peter K. H. Lau, Julie Lorent, Anna Trigos, Teresa Ward, Aparna D. Rao, Emily J. Lelliott, Karen E. Sheppard, David L. Goode, Rodney J. Hicks, Tony Tiganis, Kaylene J. Simpson, Ola Larsson, Carleen Cullinane, Vihandha O. Wickramasinghe, Richard B. Pearson, Grant A. McArthur (2019). Adaptive post-transcriptional reprogramming of metabolism limits response to targeted therapy in BRAF<sup>V600</sup> melanoma. , DOI: https://doi.org/10.1101/626952.
Preprint62 days agoAdaptive translational reprogramming of metabolism limits the response to targeted therapy in BRAFV600 melanoma
Lorey Smith, Tiffany J. Parmenter, Margarete Kleinschmidt, Eric Kusnadi, Jian Jian Kang, Claire Martin, Peter K. H. Lau, Riyaben P. Patel, Julie Lorent, David Papadopoli, Anna Trigos, Teresa Ward, Aparna D. Rao, Emily J. Lelliott, Karen E. Sheppard, David L. Goode, Rodney J. Hicks, Tony Tiganis, Kaylene J. Simpson, Ola Larsson, Benjamin J. Blyth, Carleen Cullinane, Vihandha O. Wickramasinghe, Richard B. Pearson, Grant A. McArthur (2022). Adaptive translational reprogramming of metabolism limits the response to targeted therapy in BRAFV600 melanoma. , 13(1), DOI: https://doi.org/10.1038/s41467-022-28705-x.
Article62 days ago