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Get Free AccessToll-like receptors (TLRs) are evolutionarily conserved innate receptors expressed in various immune and non-immune cells of the mammalian host. TLRs play a crucial role in defending against pathogenic microbial infection through the induction of inflammatory cytokines and type I interferons. Furthermore, TLRs also play roles in shaping pathogen-specific humoral and cellular adaptive immune responses. In this review, we describe the recent advances in pathogen recognition by TLRs and TLR signaling.
Himanshu Kumar, Taro Kawai, Akira Shizuo (2009). Toll-like receptors and innate immunity. Biochemical and Biophysical Research Communications, 388(4), pp. 621-625, DOI: 10.1016/j.bbrc.2009.08.062.
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Type
Article
Year
2009
Authors
3
Datasets
0
Total Files
0
Language
English
Journal
Biochemical and Biophysical Research Communications
DOI
10.1016/j.bbrc.2009.08.062
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