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Get Free AccessIndividuals with OCD show widespread hypoconnectivity compared to HC, with considerable interindividual variation within OCD related to previous medication use, comorbid depression, severity of anxiety, and specific OCD symptoms. General hypoconnectivity in OCD may be a good target for interventions modulating brain circuit connectivity, including transcranial magnetic stimulation.
Anders Lillevik Thorsen, Niels T. de Joode, Petra J. W. Pouwels, C. Dietz, Feng Liu, Maria Concepción García Otaduy, Bruno Pastorello, Frances Robertson, Jonathan Ipser, Seonjoo Lee, Dianne M. Hezel, Marcelo C. Batistuzzo, Marcelo Q. Hoexter, Marco Antonio Nocito Echevarria, Sheshachala Karthik, Janardhanan C. Narayanaswamy, Ganesan Venkatasubramanian, Christine Löchner, Eurı́pedes Constantino Miguel, Y.C. Janardhan Reddy, Roseli Gedanke Shavitt, Dan Joseph Stein, Melanie M. Wall, Odile A. van den Heuvel, H. Blair Simpson, Chris Vriend (2025). Resting-state functional connectivity alterations in obsessive-compulsive disorder: relationships between connectivity and clinical profiles in the Global OCD study. , DOI: https://doi.org/10.1101/2025.07.30.25332428.
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Type
Preprint
Year
2025
Authors
26
Datasets
0
Total Files
0
Language
en
DOI
https://doi.org/10.1101/2025.07.30.25332428
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