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  5. Prognostic Impact of Vitamin B6 Metabolism in Lung Cancer

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Article
en
2012

Prognostic Impact of Vitamin B6 Metabolism in Lung Cancer

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0 Files

en
2012
Vol 2 (5)
Vol. 2
DOI: 10.1016/j.celrep.2012.11.007

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Guido Guido Kroemer
Guido Guido Kroemer

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Lorenzo Galluzzi
Ilio Vitale
Laura Senovilla
+66 more

Abstract

(Cell Reports 2, 257–269; August 30, 2012) In the original version of this article, published on July 26, an error was inadvertently included in Figure 6C. In particular, Kaplan-Meier curves depicting the disease-free survival and overall survival of non-small cell lung carcinoma (NSCLC) patients followed at the MD Anderson Cancer Center (Houston, TX, USA) were swapped, due to a labeling problem with the corresponding clinical database. We have double-checked clinical data, and the amended version of the figure is provided here. The corrected figure now appears within the article online as well. This change does not influence any of the conclusions of the paper. The authors apologize for this error and for any confusion that it may have caused. Prognostic Impact of Vitamin B6 Metabolism in Lung CancerGalluzzi et al.Cell ReportsJuly 26, 2012In BriefKroemer and colleagues have discovered that vitamin B6 metabolism not only influences the response of cancer cells to the antineoplastic agent cisplatin, in vitro and in vivo, but also plays a critical role in the cellular management of multiple stress conditions. Accordingly, high expression levels of PDXK, the enzyme that generates the bioactive form of vitamin B6, constitute a good prognostic biomarker in patients with NSCLC. Full-Text PDF Open Access

How to cite this publication

Lorenzo Galluzzi, Ilio Vitale, Laura Senovilla, Ken A. Olaussen, Guillaume Pinna, Tobias Eisenberg, Aïcha Goubar, Isabelle Martins, Judith Michels, Gueorgui Kratassiouk, Didac Carmona‐Gutiérrez, Marie Scoazec, Erika Vacchelli, F. Schlemmer, Oliver Kepp, Shensi Shen, Maximilien Tailler, Mireia Niso‐Santano, Eugenia Morselli, Alfredo Criollo, Sandy Adjemian, Mohamed Jèmaà, Kariman Chaba, Claire Pailleret, Mickaël Michaud, Federico Pietrocola, Nicolas Tajeddine, Thibault De La Motte Rouge, Natália M. Araujo, Nadya Morozova, Thomas Robert, Hugues Ripoche, Frédéric Commo, Benjamin Besse, Pierre Validire, Pierre Fouret, Angélique Robin, Nicolas Dorvault, Philippe Girard, Sébastien Gouy, Patricia Pautier, Nora Jägemann, Ann‐Christin Nickel, Sabrina Marsili, Caroline Paccard, Nicolas Servant, Philippe Hupé, Carmen Behrens, Parviz Behnam‐Motlagh, Kimitoshi Kohno, Isabelle Cremer, Diane Damotte, Marco Alifano, Øivind Midttun, Per Magne Ueland, Vladimir Lazar, Philippe Dessen, Hans Zischka, Étienne Chatelut, Maria Castedo, Frank Madeo, Emmanuel Barillot, Juergen Thomale, Ignacio I. Wistuba, Catherine Sautès‐Fridman, Laurence Zitvogel, Jean‐Charles Soria, Annick Harel‐Bellan, Guido Guido Kroemer (2012). Prognostic Impact of Vitamin B6 Metabolism in Lung Cancer. , 2(5), DOI: https://doi.org/10.1016/j.celrep.2012.11.007.

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Publication Details

Type

Article

Year

2012

Authors

69

Datasets

0

Total Files

0

Language

en

DOI

https://doi.org/10.1016/j.celrep.2012.11.007

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