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Get Free AccessPrimaquine radical cure is used to treat dormant liver-stage parasites and prevent relapsing Plasmodium vivax malaria but is limited by concerns of haemolysis. We undertook a systematic review and individual patient data meta-analysis to investigate the haematological safety of different primaquine regimens for P vivax radical cure.
Megha Rajasekhar, J. A. Simpson, Benedikt Ley, Peta Edler, Cindy S. Chu, Tesfay Abreha, Ghulam Rahim Awab, J. Kevin Baird, Germana Bancone, Bridget E. Barber, Matthew J. Grigg, Jimee Hwang, Harin Karunajeewa, Marcus Lacerda, Simone Ladeia-Andrade, Alejandro Llanos‐Cuentas, Sasithon Pukrittayakamee, Komal Raj Rijal, Kavitha Saravu, Inge Sutanto, Walter Taylor, Kamala Thriemer, James A Watson, Philippe J. Guérin, Sir Nicholas White, Ric N. Price, Robert J. Commons, Bipin Adhikari, Mohammad Shafiul Alam, Nicholas M. Anstey, Ashenafi Assefa, Sarah Boyd, Nguyen Hoang Chau, Nicholas Day, Tamiru Shibiru Degaga, Arjen M. Dondorp, Marcelo U. Ferreira, Prakash Ghimire, Justin A. Green, Wasif Ali Khan, Gavin Koh, Asrat Hailu Mekuria, Mohammad Nader Naadim, Erni Juwita Nelwan, François Nosten, Ayodhia Pitaloka Pasaribu, David J. Price, Kasia Stepniewska, Lorenz von Seidlein, Timothy William, Charles J. Woodrow, Adugna Woyessa (2023). Primaquine dose and the risk of haemolysis in patients with uncomplicated Plasmodium vivax malaria: a systematic review and individual patient data meta-analysis. The Lancet Infectious Diseases, 24(2), pp. 184-195, DOI: 10.1016/s1473-3099(23)00431-0.
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Type
Article
Year
2023
Authors
52
Datasets
0
Total Files
0
Language
English
Journal
The Lancet Infectious Diseases
DOI
10.1016/s1473-3099(23)00431-0
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