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Get Free AccessAbstract With the development of engineered nanomaterials and nanomedicines, utilization of nanomaterials to generate excessive reactive oxygen species under exogenous ultrasound (US) irradiation for realizing disease therapy, namely sonodynamic therapy (SDT), has attracted widespread attention. Compared with traditional photodynamic therapy, US shows deeper tissue penetration to reach deep‐seated location. However, the development of high‐efficiency sonosensitizers remains one of the gravest challenges in current related research and future clinical application. Latterly, benefiting from the piezotronic and piezo‐phototronic effects, novel sonosensitizers based on piezoelectric semiconductor (PS) nanomaterials have exhibited inspiring application prospects in SDT. In this review, we outline the structures and physicochemical properties of PS nanomaterials that has potential applications in SDT, and introduce the presumed mechanisms of PS nanomaterials in SDT. Then, the latest research progress of PS nanomaterials as sonosensitizers in cancer therapy and antibacterial applications are summarized. Finally, the existing challenges and future development trends in this field are prospected.
Yunchao Zhao, Tian Huang, Xiaodi Zhang, Yuanbo Cui, Lili Zhang, Linlin Li, Zhong Lin Wang (2023). Piezotronic and piezo‐phototronic effects on sonodynamic disease therapy. , 1(1), DOI: https://doi.org/10.1002/bmm2.12006.
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Type
Article
Year
2023
Authors
7
Datasets
0
Total Files
0
Language
en
DOI
https://doi.org/10.1002/bmm2.12006
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