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Get Free AccessHigh levels of intracellular poly(ADP-ribose) (PAR) resulting from an elevated activity of PAR polymerase-1 (PARP1) correlate with poor infiltration of non-small cell lung cancers by cytotoxic T lymphocytes and dismal patient prognosis. Preclinical experimentation now demonstrates that PARP1 inhibition in cancer cells mediates strong immunostimulatory effects.
Pan Juncheng, Antoine Lafarge, Guido Guido Kroemer, Maria Castedo (2022). PARP1 inhibition elicits immune responses against non-small cell lung cancer. , 11(1), DOI: https://doi.org/10.1080/2162402x.2022.2111915.
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Type
Article
Year
2022
Authors
4
Datasets
0
Total Files
0
Language
en
DOI
https://doi.org/10.1080/2162402x.2022.2111915
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