0 Datasets
0 Files
Get instant academic access to this publication’s datasets.
Yes. After verification, you can browse and download datasets at no cost. Some premium assets may require author approval.
Files are stored on encrypted storage. Access is restricted to verified users and all downloads are logged.
Yes, message the author after sign-up to request supplementary files or replication code.
Join 50,000+ researchers worldwide. Get instant access to peer-reviewed datasets, advanced analytics, and global collaboration tools.
✓ Immediate verification • ✓ Free institutional access • ✓ Global collaborationJoin our academic network to download verified datasets and collaborate with researchers worldwide.
Get Free AccessOver the last decade, the composition of the gut microbiota has been found to correlate with the outcomes of cancer patients treated with immunotherapy. Accumulating evidence points to the various mechanisms by which intestinal bacteria act on distal tumors and how to harness this complex ecosystem to circumvent primary resistance to immune checkpoint inhibitors. Here, we review the state of the microbiota field in the context of melanoma, the recent breakthroughs in defining microbial modes of action, and how to modulate the microbiota to enhance response to cancer immunotherapy. The host-microbe interaction may be deciphered by the use of "omics" technologies, and will guide patient stratification and the development of microbiota-centered interventions. Efforts needed to advance the field and current gaps of knowledge are also discussed.
Bertrand Routy, Tanisha Jackson, Laura Mählmann, Christina K. Baumgartner, Martin J. Blaser, Allyson L. Byrd, Nathalie Corvaı̈a, Kasey L. Couts, Diwakar Davar, Lisa Derosa, Howard C. Hang, Geke A.P. Hospers, Morten L. Isaksen, Guido Guido Kroemer, Florent Malard, Kathy D. McCoy, Marlies Meisel, Sumanta K. Pal, Ze’ev A. Ronai, Eran Segal, Gregory D. Sepich‐Poore, Fyza Shaikh, Randy F. Sweis, Giorgio Trinchieri, Marcel R.M. van den Brink, Rinse K. Weersma, Katrine Whiteson, Liping Zhao, Jennifer L. McQuade, Hassane M. Zarour, Laurence Zitvogel (2023). Melanoma and microbiota: Current understanding and future directions. , 42(1), DOI: https://doi.org/10.1016/j.ccell.2023.12.003.
Datasets shared by verified academics with rich metadata and previews.
Authors choose access levels; downloads are logged for transparency.
Students and faculty get instant access after verification.
Type
Article
Year
2023
Authors
31
Datasets
0
Total Files
0
Language
en
DOI
https://doi.org/10.1016/j.ccell.2023.12.003
Access datasets from 50,000+ researchers worldwide with institutional verification.
Get Free Access
