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Get Free AccessFerroptosis, characterized by lipid peroxidation-mediated cell demise, is governed by a nuanced interplay of lipid species influencing its vulnerability. Two recent publications in Nature discovered 7-dehydrocholesterol, a cholesterol precursor, as a radical-trapping antioxidant that can suppress ferroptosis, thereby presenting a novel metabolic target to improve ferroptosis-related cancer therapy.
Ruoxi Zhang, Guido Guido Kroemer, Daolin Tang (2024). Lipid-derived radical-trapping antioxidants suppress ferroptosis. , 3(2), DOI: https://doi.org/10.1093/lifemeta/loae008.
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Type
Article
Year
2024
Authors
3
Datasets
0
Total Files
0
Language
en
DOI
https://doi.org/10.1093/lifemeta/loae008
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