Initial and Delayed Onset of Acute Respiratory Failure: Factors Associated with Development and Outcome

Suzana Margareth Lobo; Francisco Ricardo Marques Lobo; Flavio Lopes-Ferreira; Daliana Peres Bota; Christian Mélot; Jean Louis Vincent

doi:10.1213/01.ane.0000237433.00877.5a

Verified authors • Institutional access • DOI aware

50,000+ researchers120,000+ datasets90% satisfaction

Article

2006

Initial and Delayed Onset of Acute Respiratory Failure: Factors Associated with Development and Outcome

0 Datasets

0 Files

2006

Vol 103 (5)

Vol. 103

DOI: 10.1213/01.ane.0000237433.00877.5a

Get instant academic access to this publication’s datasets.

Create free account How it works

Frequently asked questions

Is access really free for academics and students?

Yes. After verification, you can browse and download datasets at no cost. Some premium assets may require author approval.

How is my data protected?

Files are stored on encrypted storage. Access is restricted to verified users and all downloads are logged.

Can I request additional materials?

Yes, message the author after sign-up to request supplementary files or replication code.

Advance your research today

Join 50,000+ researchers worldwide. Get instant access to peer-reviewed datasets, advanced analytics, and global collaboration tools.

Get free academic access Learn more

✓ Immediate verification • ✓ Free institutional access • ✓ Global collaboration

In a prospective observational study of 1038 adult admissions to a 31-bed medical/surgical intensive care unit (ICU), acute respiratory failure (ARF, defined as a Pao(2)/Fio(2) ratio 48 h after ICU admission) in 49 (16%). On admission, the cardiovascular sequential organ failure assessment (SOFA) score was higher in initial than in delayed onset ARF (1.1 +/- 1.5 vs 0.6 +/- 1.2, P < 0.05). High admission serum C-reactive protein concentrations (OR 1.08, 95% CI 1.04-1.12, P = 0.0001) and SOFA scores (OR 1.20, 95% CI 1.08-1.33, P = 0.0007) were the factors independently associated with initial ARF, and a low Glasgow coma scale (GCS) score (OR 1.13, 95% CI 1.04-1.21, P = 0.0018) was associated with delayed onset ARF. In initial ARF, a high SOFA score (OR 1.24, 95% CI 1.12-1.38, P = 0.0001) and a low GCS score (OR 0.89, 95% CI 0.83-0.96, P = 0.0013) on admission, and in delayed onset ARF, a low GCS score at 48 h (OR 0.67, 95% CI 0.54-0.84, P = 0.0011) were independently associated with death. The mortality rate was similar for initial and delayed onset ARF.

Initial and Delayed Onset of Acute Respiratory Failure: Factors Associated with Development and Outcome

Frequently asked questions

Is access really free for academics and students?

How is my data protected?

Can I request additional materials?

Advance your research today

Initial and Delayed Onset of Acute Respiratory Failure: Factors Associated with Development and Outcome

Frequently asked questions

Is access really free for academics and students?

How is my data protected?

Can I request additional materials?

Advance your research today

Access Research Data

This PDF is not available in different languages.

Jean Louis Vincent

Abstract

How to cite this publication

Related publications

Why join Raw Data Library?

Quality

Control

Free for Academia

Publication Details

Join Research Community