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Get Free AccessIn type 2 diabetes, the Ala allele protects from worsening albuminuria and new-onset microalbuminuria, and ACE inhibition blunts the excess risk of microalbuminuria associated with the Pro/Pro genotype. Evaluating Pro12Ala polymorphism may help identifying patients at risk who may benefit the most from early renoprotective therapy.
Salvatore De Cosmo, Nicola Motterlini, Sabrina Prudente, Fabio Pellegrini, Roberto Trevisan, Antonio Bossi, Giuseppe Remuzzi, Vincenzo Trischitta, Piero Ruggenenti (2009). Impact of the <i>PPAR</i>-γ<i>2</i> Pro12Ala Polymorphism and ACE Inhibitor Therapy on New-Onset Microalbuminuria in Type 2 Diabetes: Evidence From BENEDICT. , 58(12), DOI: https://doi.org/10.2337/db09-0407.
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Type
Article
Year
2009
Authors
9
Datasets
0
Total Files
0
Language
en
DOI
https://doi.org/10.2337/db09-0407
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