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Get Free AccessBMP4 acts downstream of HIF-1 and mediates hypoxia-induced up-regulation of TRPC, leading to increased basal [Ca(2+)]i in PASMCs, promoting CHPH pathogenesis.
Jian Wang, Xin Fu, Kai Yang, Jiang Qian, Yuqin Chen, Jing Jia, Xin Duan, Elizabeth W. Wang, Jianxing He, Pixin Ran, Nanshan Zhong, Gregg L. Friedman, Wenju Lu (2015). Hypoxia inducible factor-1-dependent up-regulation of BMP4 mediates hypoxia-induced increase of TRPC expression in PASMCs. , 107(1), DOI: https://doi.org/10.1093/cvr/cvv122.
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Type
Article
Year
2015
Authors
13
Datasets
0
Total Files
0
Language
en
DOI
https://doi.org/10.1093/cvr/cvv122
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