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  5. Human sebum requires de novo lipogenesis, which is increased in acne vulgaris and suppressed by acetyl-CoA carboxylase inhibition

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Article
en
2019

Human sebum requires de novo lipogenesis, which is increased in acne vulgaris and suppressed by acetyl-CoA carboxylase inhibition

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0 Files

en
2019
Vol 11 (492)
Vol. 11
DOI: 10.1126/scitranslmed.aau8465

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Marc Hellerstein
Marc Hellerstein

University of California, Berkeley

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William P. Esler
Gregory J. Tesz
Marc Hellerstein
+20 more

Abstract

De novo lipogenesis is essential for human sebum production, and increased lipogenic flux accounts for excessive sebum production in acne vulgaris.

How to cite this publication

William P. Esler, Gregory J. Tesz, Marc Hellerstein, Carine Beysen, Raja K. Sivamani, Scott Turner, Steven M. Watkins, Paul A. Amor, Santos Carvajal‐Gonzalez, Frank J. Geoly, Kathleen Biddle, Julie J. Purkal, Mark Fitch, Clare Buckeridge, Annette M. Silvia, David A. Griffith, Matthew Gorgoglione, Lauren A. Hassoun, Suzana S. Bosanac, Nicholas B. Vera, Tim Rolph, Jeffrey A. Pfefferkorn, Gabriele E. Sonnenberg (2019). Human sebum requires de novo lipogenesis, which is increased in acne vulgaris and suppressed by acetyl-CoA carboxylase inhibition. , 11(492), DOI: https://doi.org/10.1126/scitranslmed.aau8465.

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Publication Details

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Article

Year

2019

Authors

23

Datasets

0

Total Files

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Language

en

DOI

https://doi.org/10.1126/scitranslmed.aau8465

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