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  5. High Levels of Coagulation Factor XI as a Risk Factor for Venous Thrombosis

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Article
English
2000

High Levels of Coagulation Factor XI as a Risk Factor for Venous Thrombosis

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0 Files

English
2000
New England Journal of Medicine
Vol 342 (10)
DOI: 10.1056/nejm200003093421004

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Frits R. Rosendaal
Frits R. Rosendaal

Leiden University

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Joost C.M. Meijers
Winnie L.H. Tekelenburg
Bonno N. Bouma
+2 more

Abstract

Factor XI, a component of the intrinsic pathway of coagulation, contributes to the generation of thrombin, which is involved in both the formation of fibrin and protection against fibrinolysis. A deficiency of factor XI is associated with bleeding, but a role of high factor XI levels in thrombosis has not been investigated.

How to cite this publication

Joost C.M. Meijers, Winnie L.H. Tekelenburg, Bonno N. Bouma, Rogier M. Bertina, Frits R. Rosendaal (2000). High Levels of Coagulation Factor XI as a Risk Factor for Venous Thrombosis. New England Journal of Medicine, 342(10), pp. 696-701, DOI: 10.1056/nejm200003093421004.

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Publication Details

Type

Article

Year

2000

Authors

5

Datasets

0

Total Files

0

Language

English

Journal

New England Journal of Medicine

DOI

10.1056/nejm200003093421004

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