Genetic variation influencing DNA methylation provides new insights into the molecular pathways regulating genomic function - Selected Supplementary Tables

Selected Supplementary Tables - ST5, 7, 8 and 9 Supplementary Table 5. Cosmopolitan results. Cosmopolitan SNP-CpG associations identified through genome-wide association amongst Europeans and South Asians. Supplementary Table 7. Cross-tissue replication. Results for further testing of the 11,165,559 cosmopolitan SNP-CpG associations identified (by genome-wide association in blood), in 4 isolated white cell subsets (CD4+ lymphocytes, CD8+ lymphocytes, monocytes and neutrophils), in adipocytes isolated from subcutaneous adipose tissue or visceral adipose tissue, and in whole adipose tissue. Supplementary Table 8. Conditional analysis. Results of conditional analysis to identify SNPs independently associated with each of the ~360K CpG sites tested. Supplementary Table 9. Sentinel SNPs and CpGs. Results of R2 pruning and locus merging to identify discrete genetic and methylation loci that are associated, and their respective sentinel SNPs and sentinel CpG sites. Other files (e.g. annotation files and 'intermediate' processing files) referenced in our code are also provided.

How to cite this publication

Johann S. Hawe, Rory Wilson, Katharina T. Schmid, Zhou Li, Lakshmi Lakshmanan, Benjamin Lehne, William R. Scott, Matthias Wielscher, Yik Weng Yew, Clemens Baumbach, Dominic P Lee, Eirini Marouli, Manon Bernard, Liliane Pfeiffer, Pamela R. Matías‐García, Matias Autio, Stéphane Bourgeois, Christian Herder, Ville Karhunen, Thomas Meitinger, Holger Prokisch, Wolfgang Rathmann, Michael Roden, Sylvain Sebért, Jean Shin, Konstantin Strauch, Weihua Zhang, Wilson LW Tan, Stefanie M. Hauck, Juliane Merl‐Pham, Harald Grallert, Eudes G. V. Barbosa, MuTHER Consortium, Thomas Illig, Annette Peters, Tomáš Paus, Zdenka Pausová, Panos Deloukas, Roger Foo, Paul M Ridker, Jaspal S. Kooner, Marie Loh, Matthias Heinig, Christian Gieger, Mélanie Waldenberger, John C. ChambersGenetic variation influencing DNA methylation provides new insights into the molecular pathways regulating genomic function - Selected Supplementary Tables. , DOI: https://doi.org/10.5281/zenodo.5053122.

Related publications

Why join Raw Data Library?

Quality

Datasets shared by verified academics with rich metadata and previews.

Control

Authors choose access levels; downloads are logged for transparency.

Free for Academia

Students and faculty get instant access after verification.

Publication Details

Type

Dataset

Authors

46

Datasets

0

Total Files

0

Language

en

DOI

https://doi.org/10.5281/zenodo.5053122

Join Research Community

Access datasets from 50,000+ researchers worldwide with institutional verification.

Get Free Access

Frequently asked questions

Is access really free for academics and students?

Yes. After verification, you can browse and download datasets at no cost. Some premium assets may require author approval.

How is my data protected?

Files are stored on encrypted storage. Access is restricted to verified users and all downloads are logged.

Can I request additional materials?

Yes, message the author after sign-up to request supplementary files or replication code.

Advance your research today

Join 50,000+ researchers worldwide. Get instant access to peer-reviewed datasets, advanced analytics, and global collaboration tools.

Get free academic access Learn more

✓ Immediate verification • ✓ Free institutional access • ✓ Global collaboration