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  5. Figure S7 from ERBB4-Mediated Signaling Is a Mediator of Resistance to PI3K and BTK Inhibitors in B-cell Lymphoid Neoplasms

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Preprint
en
2025

Figure S7 from ERBB4-Mediated Signaling Is a Mediator of Resistance to PI3K and BTK Inhibitors in B-cell Lymphoid Neoplasms

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en
2025
DOI: 10.1158/1535-7163.28547992

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Manel Esteller
Manel Esteller

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Alberto J. Arribas
Sara Napoli
Luciano Cascione
+21 more

Abstract

<p>(A) Immunoblotting was performed to measure protein levels in parental and resistant clones for pAKT/AKT and pERK/ERK in three independent experiments. GAPDH was used as a loading control. (B) Protein quantification was done normalizing first to GAPDH and then to total protein. Barplot represents the quantification in each of the independent experiments, parental in grey, resistant in red. Median and standard error of the mean for parental and resistant levels in the three experiments. Moderated t-test was performed to determine statistically significance (p<0.05).</p>

How to cite this publication

Alberto J. Arribas, Sara Napoli, Luciano Cascione, Laura Barnabei, Giulio Sartori, Eleonora Cannas, Eugenio Gaudio, Chiara Tarantelli, Afua A. Mensah, Filippo Spriano, Antonella Zucchetto, Francesca Maria Rossi, Andrea Rinaldi, Manuel Castro de Moura, Sandra Jovic, Roberta Bordone Pittau, Anastasios Stathis, Georg Stüssi, Valter Gattei, Jennifer R. Brown, Manel Esteller, Emanuele Zucca, Davide Rossi, Francesco Bertoni (2025). Figure S7 from ERBB4-Mediated Signaling Is a Mediator of Resistance to PI3K and BTK Inhibitors in B-cell Lymphoid Neoplasms. , DOI: https://doi.org/10.1158/1535-7163.28547992.

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Publication Details

Type

Preprint

Year

2025

Authors

24

Datasets

0

Total Files

0

Language

en

DOI

https://doi.org/10.1158/1535-7163.28547992

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