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Get Free Access<p>Mutational landscape of patients with the studied MDS. <b>A,</b> Summary of the study workflow. <b>B,</b> Oncoprint indicating the mutations present in the patient cohort, at diagnosis and after AZA treatment, colored by coding impact. Multi-hit means presence of more than one mutation of same coding impact (missense, nonsense, or frameshift) in the same gene. <b>C,</b> UpSet plot illustrating the exclusive intersection of mutated pathways at diagnosis in patients with MDS. The patients are colored according to the response status (green, responders; magenta, nonresponders). </p>
Ignacio Campillo‐Marcos, Marta Casado-Peláez, Verónica Dávalos, Gerardo Ferrer, Caterina Mata, Elisabetta Mereu, Gaël Roué, David Valcárcel, Antonieta Molero, Lurdes Zamora, Blanca Xicoy, Laura Palomo, Pamela Acha, Ana Manzanares, Magnus Tobiasson, Eva Hellström‐Lindberg, Françesc Solé, Manel Esteller (2024). FIGURE 1 from Single-cell Multiomics Analysis of Myelodysplastic Syndromes and Clinical Response to Hypomethylating Therapy. , DOI: https://doi.org/10.1158/2767-9764.25206479.v1.
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Type
Preprint
Year
2024
Authors
18
Datasets
0
Total Files
0
Language
en
DOI
https://doi.org/10.1158/2767-9764.25206479.v1
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