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Get Free AccessWe identified 4 clinically relevant disability worsening phenotypes in relapse-onset MS, primarily driven by PIRA, with greater CNS involvement linked to early and rapid progression. Despite reliance on EDSS alone, these phenotypes may inform personalized treatment and response assessment.
Ermelinda De Meo, Ilaria Addazio, Emilio Portaccio, Raffaello Bonacchi, M. Betti, Francesco Patti, Simone Guerrieri, Matteo Foschi, Diana Ferraro, Pietro Annovazzi, Vincenzo Brescia Morra, Carla Tortorella, Alessandra Lugaresi, Federico Camilli, Carlo Pozzilli, Paola Perini, Franco Granella, Giovanna De Luca, María Trojano, Marika Vianello, Silvia Romano, Eleonora Cocco, Giacomo Lus, Alessia Di Sapio, Maria A. Rocca, Marta Simone, Pietro Iaffaldano, Massimo Filippi, María Trojano, Maria Pia Amato (2025). Disability Worsening Phenotypes in Multiple Sclerosis and Impact of Disease-Modifying Treatments. , 105(12), DOI: https://doi.org/10.1212/wnl.0000000000214408.
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Type
Article
Year
2025
Authors
30
Datasets
0
Total Files
0
Language
en
DOI
https://doi.org/10.1212/wnl.0000000000214408
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