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Get Free AccessPhysicians are not always comfortable deferring treatment of a stenosis in the left anterior descending (LAD) artery because of the perception that there is a high risk of major adverse cardiac events (MACE). The authors describe, using the DEFINE-FLAIR (Functional Lesion Assessment of Intermediate Stenosis to Guide Revascularisation) trial, MACE rates when LAD lesions are deferred, guided by physiological assessment using fractional flow reserve (FFR) or the instantaneous wave-free ratio (iFR).
Sayan Sen, Yousif Ahmad, Hakim-Moulay Dehbi, James P. Howard, Juan F. Iglesias, Rasha Al‐Lamee, Ricardo Petraco, Sukhjinder Nijjer, Ravinay Bhindi, Sam J. Lehman, D. Walters, James Sapontis, Luc Janssens, Christiaan Vrints, Ahmed Khashaba, Mika Laine, Éric Van Belle, Florian Krackhardt, Waldemar Bojara, Olaf Göing, Tobias Härle, Ciro Indolfi, Giampaolo Niccoli, Flavio Ribichini, Nobuhiro Tanaka, Hiroyoshi Yokoi, Hiroaki Takashima, Yuetsu Kikuta, Andrejs Ērglis, Hugo Vinhas, Pedro Canas Silva, Sérgio Bravo Baptista, Ali Alghamdi, Farrel Hellig, Bon‐Kwon Koo, Chang‐Wook Nam, Eun‐Seok Shin, Joon‐Hyung Doh, Salvatore Brugaletta, Eduardo Alegría‐Barrero, Martijin Meuwissen, Jan J. Piek, Niels van Royen, Murat Sezer, Carlo Di Mario, Robert Gerber, Iqbal Malik, Andrew S.P. Sharp, Suneel Talwar, Kare Tang, Habib Samady, John D. Altman, Arnold H. Seto, Jasvindar Singh, Allen Jeremias, Hitoshi Matsuo, Rajesh Kharbanda, Manesh R. Patel, Patrick W. Serruys, Javier Escaned, Justin E. Davies (2019). Clinical Events After Deferral of LAD Revascularization Following Physiological Coronary Assessment. Journal of the American College of Cardiology, 73(4), pp. 444-453, DOI: 10.1016/j.jacc.2018.10.070.
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Type
Article
Year
2019
Authors
61
Datasets
0
Total Files
0
Language
English
Journal
Journal of the American College of Cardiology
DOI
10.1016/j.jacc.2018.10.070
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