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Get Free AccessConventional photodynamic therapy (PDT) suffers from aggregation-caused quenching and high oxygen dependence. Herein, we report a platinum (Pt)-coordinated photosensitizer (TPAQPt) for hypoxia-tolerant PDT. Inheriting aggregation-induced emission (AIE) features, high spin orbital coupling and intramolecular charge transfer ability, TPAQPt exhibits robust type I reactive oxygen species generation and a promising antitumor PDT effect.
Ping Liang, Wenjing Li, Ben Zhong Tang, Guangxue Feng (2025). An AIE-active platinum complex for enhanced photodynamic therapy. , 62(5), DOI: https://doi.org/10.1039/d5cc05324b.
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Type
Article
Year
2025
Authors
4
Datasets
0
Total Files
0
Language
en
DOI
https://doi.org/10.1039/d5cc05324b
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