Abstract MP13: Types and Sources of Dietary Fatty Acids and Markers of Diabetes Risk: The NEO Study

Introduction: Insufficient and inconsistent evidence is available on the association between dietary fatty acids and the development of type 2 diabetes. The objective of this study was to examine associations of the intake of total fat, saturated fat (SFA), mono- and poly-unsaturated fat (MUFA, PUFA), trans fat (TFA), and their food sources (dairy, meat, plant) with markers of glucose metabolism and diabetes risk. Hypothesis: We hypothesized that different types of fatty acids are differentially associated with markers of diabetes risk. Methods: We analysed baseline data of 5,675 non-diabetic men and women, aged 45 to 65 years, from the Netherlands Epidemiology of Obesity (NEO) study. Habitual intake of fatty acids was measured using a 125-item semi-quantitative food frequency questionnaire. Glucose and insulin concentrations were measured before, and 30 and 150 minutes after a standardized liquid mixed meal, and HOMA-IR, HOMA-B and Disposition index were calculated. Linear regression models were adjusted...